BRENDA - Enzyme Database
show all sequences of 3.1.26.12

RNase E and the other constituents of the RNA degradosome are components of the bacterial cytoskeleton

Taghbalout, A.; Rothfield, L.; Proc. Natl. Acad. Sci. USA 104, 1667-1672 (2007)

Data extracted from this reference:

Cloned(Commentary)
Cloned (Commentary)
Organism
gene rne, expression of wild-type and mutant enzymes in Escherichia coli and in the Saccharomyces cerevisiae two-hybrid system
Escherichia coli
Engineering
Protein Variants
Commentary
Organism
additional information
the constructed rne mutant strains AT8, i.e. Prne-rne1-417, and AT14, i.e. Prne-rne1-659, show loss of the helical protein organization and reduced activity, AT8 cells grow slowly and show a defect in cell division as shown by a mixed population ranging from normal-length cells to long filaments, AT8 cells exhibit a chromosome segregation defect, phenotypes, overview
Escherichia coli
Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
cytoskeleton
RNase E and the other constituents of the RNA degradosome are components of the bacterial cytoskeleton, degradosome components, i.e. RNase E, helicase B, polynucleotide hosphorylase, and enolase, are organized as helical filamentous structures that coil around the length of the cell. Formation of the RNaseE cytoskeletal-like structure requires an internal domain of the protein that does not include the domains required for any of its known interactions or the minimal domain required for endonuclease activity, but is independent of MreB and MinD cytoskeletal structures, mechanism of assembly, overview
Escherichia coli
5856
-
additional information
the enzyme is the main part of the RNA degradosome
Escherichia coli
-
-
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
additional information
Escherichia coli
RNaseE, as the main component of the RNA degradosome of Escherichia coli, plays an essential role in RNA processing and decay
?
-
-
?
Organism
Organism
UniProt
Commentary
Textmining
Escherichia coli
-
gene rne
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
additional information
RNaseE, as the main component of the RNA degradosome of Escherichia coli, plays an essential role in RNA processing and decay
689760
Escherichia coli
?
-
-
-
?
Synonyms
Synonyms
Commentary
Organism
RNase E
-
Escherichia coli
Cloned(Commentary) (protein specific)
Commentary
Organism
gene rne, expression of wild-type and mutant enzymes in Escherichia coli and in the Saccharomyces cerevisiae two-hybrid system
Escherichia coli
Engineering (protein specific)
Protein Variants
Commentary
Organism
additional information
the constructed rne mutant strains AT8, i.e. Prne-rne1-417, and AT14, i.e. Prne-rne1-659, show loss of the helical protein organization and reduced activity, AT8 cells grow slowly and show a defect in cell division as shown by a mixed population ranging from normal-length cells to long filaments, AT8 cells exhibit a chromosome segregation defect, phenotypes, overview
Escherichia coli
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
cytoskeleton
RNase E and the other constituents of the RNA degradosome are components of the bacterial cytoskeleton, degradosome components, i.e. RNase E, helicase B, polynucleotide hosphorylase, and enolase, are organized as helical filamentous structures that coil around the length of the cell. Formation of the RNaseE cytoskeletal-like structure requires an internal domain of the protein that does not include the domains required for any of its known interactions or the minimal domain required for endonuclease activity, but is independent of MreB and MinD cytoskeletal structures, mechanism of assembly, overview
Escherichia coli
5856
-
additional information
the enzyme is the main part of the RNA degradosome
Escherichia coli
-
-
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
additional information
Escherichia coli
RNaseE, as the main component of the RNA degradosome of Escherichia coli, plays an essential role in RNA processing and decay
?
-
-
?
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
additional information
RNaseE, as the main component of the RNA degradosome of Escherichia coli, plays an essential role in RNA processing and decay
689760
Escherichia coli
?
-
-
-
?
Other publictions for EC 3.1.26.12
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
751494
Bandyra
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Caulobacter vibrioides, Escherichia coli, Escherichia coli K12
Microbiol. Spectr.
6
0000
2018
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2
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751555
Bandyra
Substrate recognition and aut ...
Escherichia coli, Escherichia coli K12
Mol. Cell
72
275-285.e4
2018
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1
1
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751679
Behler
The host-encoded RNase e endo ...
Synechocystis sp. PCC 6803
Nat. Microbiol.
3
367-377
2018
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1
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752062
Bayas
Spatial organization and dyna ...
Caulobacter vibrioides
Proc. Natl. Acad. Sci. USA
115
E3712-E3721
2018
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751506
Baumgardt
RNase E and RNase J are neede ...
Sinorhizobium meliloti, Sinorhizobium meliloti Rm2011
Microbiology
163
570-583
2017
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6
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751553
Chao
InVivo cleavage map illuminat ...
Salmonella enterica
Mol. Cell
65
39-51
2017
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749757
Tamura
PpsA-mediated alternative pat ...
Escherichia coli, Escherichia coli K12
Arch. Microbiol.
198
409-421
2016
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12
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1
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750371
Kim
Functional Analysis of Vibrio ...
Vibrio vulnificus
Curr. Microbiol.
72
716-722
2016
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1
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9
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751080
Richards
Distinct requirements for 5-m ...
Escherichia coli
J. Biol. Chem.
291
5038-5048
2016
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751731
Mohanty
Endonucleolytic cleavages by ...
Escherichia coli, Escherichia coli MG1693
Nucleic Acids Res.
44
6350-6362
2016
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8
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1
1
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752160
Sulthana
Elucidation of pathways of ri ...
Escherichia coli, Escherichia coli K12
RNA
22
1163-1171
2016
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1
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730503
Clarke
Direct entry by RNase E is a m ...
Escherichia coli
Nucleic Acids Res.
42
11733-11751
2015
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1
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750701
Qi
Rapid degradation of host mRN ...
Escherichia coli, Escherichia coli K12
Genetics
201
977-987
2015
1
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13
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1
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750962
Thompson
Altering the divalent metal i ...
Escherichia coli, Escherichia coli K12
J. Bacteriol.
197
477-482
2015
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2
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2
5
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1
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751598
Ait-Bara
RNA degradosomes in bacteria ...
Escherichia coli, Escherichia coli K12
Mol. Microbiol.
97
1021-1135
2015
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1
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14
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2
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751600
Hammarloef
Turnover of mRNAs is one of t ...
Salmonella enterica subsp. enterica serovar Typhimurium, Salmonella enterica subsp. enterica serovar Typhimurium LT2
Mol. Microbiol.
98
34-45
2015
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1
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729757
Martinez
Ribonuclease PH interacts with ...
Escherichia coli, Escherichia coli CA244
FEMS Microbiol. Lett.
355
51-60
2014
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729937
Baumgardt
RNase E affects the expression ...
Sinorhizobium meliloti, Sinorhizobium meliloti Rm2011
J. Bacteriol.
196
1435-1447
2014
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730512
Kime
Adjacent single-stranded regio ...
Escherichia coli
Nucleic Acids Res.
42
4577-4589
2014
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1
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5
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730781
Kim
Modulation of RNase E activity ...
Escherichia coli, Escherichia coli KSL2003
PLoS ONE
9
e90610
2014
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2
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2
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730942
Zhang
RNase E forms a complex with p ...
Anabaena sp., Synechocystis sp., Anabaena sp. PCC 7120
RNA
20
568-579
2014
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2
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6
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34
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2
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729037
Viegas
The virulence of Salmonella en ...
Salmonella enterica
Appl. Environ. Microbiol.
79
6124-6133
2013
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1
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7
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1
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729924
Tamura
Nutrient dependence of RNase E ...
Escherichia coli, Escherichia coli MG1655
J. Bacteriol.
195
1133-1141
2013
-
-
-
-
-
-
-
-
-
-
-
2
-
34
-
-
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-
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2
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-
2
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-
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-
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2
2
-
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-
730699
Manasherob
Ribonuclease E modulation of t ...
Escherichia coli
PLoS ONE
7
e38426
2012
-
-
-
-
-
-
-
-
-
-
-
1
-
6
-
-
-
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1
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-
1
-
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-
-
-
-
-
-
-
-
2
2
-
-
-
730815
Murashko
Membrane binding of Escherichi ...
Escherichia coli
Proc. Natl. Acad. Sci. USA
109
7019-7024
2012
-
-
1
-
-
1
-
-
4
-
-
1
-
7
-
-
-
-
-
-
-
-
1
-
2
-
-
-
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-
-
-
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-
1
-
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1
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-
-
4
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
713995
Maeda
Corynebacterium glutamicum RNa ...
Corynebacterium glutamicum, Corynebacterium glutamicum ATCC 31831
Arch. Microbiol.
194
65-73
2011
-
-
-
-
-
-
-
-
-
-
-
-
-
11
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
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-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
3
-
-
-
714789
Lee
Studies on a Vibrio vulnificus ...
Vibrio vulnificus
Curr. Microbiol.
62
861-865
2011
-
-
1
-
1
-
-
-
-
-
2
-
-
9
-
-
-
-
-
-
-
-
2
1
1
-
-
-
-
-
-
-
-
-
-
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1
-
-
1
-
-
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-
-
-
2
-
-
-
-
-
-
-
-
-
2
1
-
-
-
-
-
-
-
-
-
1
1
-
-
-
715390
Hammarloef
Temperature-sensitive mutants ...
Salmonella enterica
J. Bacteriol.
193
6639-6650
2011
-
-
-
-
14
-
-
-
-
-
-
-
-
6
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
14
-
-
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-
-
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-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
716262
Ikeda
Hfq binding at RhlB-recognitio ...
Escherichia coli
Mol. Microbiol.
79
419-432
2011
-
-
1
-
2
-
1
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
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1
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2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
716266
Garrey
Roles of the 5-phosphate senso ...
Escherichia coli
Mol. Microbiol.
80
1613-1624
2011
-
-
1
-
10
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
10
-
-
-
-
-
-
-
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-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
2
-
-
-
716388
Stazic
Antisense RNA protects mRNA fr ...
Prochlorococcus sp., Prochlorococcus sp. MED4
Nucleic Acids Res.
39
4890-4899
2011
-
1
1
-
-
-
-
-
-
1
-
-
-
6
-
-
1
-
-
-
-
-
2
-
1
1
-
-
-
1
-
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
2
-
1
-
-
-
1
-
-
-
-
1
1
-
-
-
710001
Kime
Rapid cleavage of RNA by RNase ...
Escherichia coli
Mol. Microbiol.
76
590-604
2010
-
-
1
-
2
-
-
3
-
-
-
-
-
3
-
-
1
-
-
-
-
1
5
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
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2
-
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-
3
-
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-
-
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-
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1
-
-
-
1
5
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
713614
Nurmohamed
Molecular recognition between ...
Escherichia coli
Acta Crystallogr. Sect. D
66
1036-1040
2010
-
-
-
2
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
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-
-
2
-
-
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-
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2
-
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-
-
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-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
716898
Chung
Single amino acid changes in t ...
Escherichia coli
RNA
16
1371-1385
2010
-
-
-
-
1
-
-
-
-
-
-
3
-
5
-
-
-
-
-
-
-
-
3
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
4
4
-
-
-
691958
Lee
Effects of Escherichia coli Rr ...
Escherichia coli, Escherichia coli KSL2003
Curr. Microbiol.
58
349-353
2009
-
-
-
-
-
-
3
-
-
-
-
-
-
8
-
-
-
-
-
-
-
-
2
-
1
-
-
-
-
-
-
-
-
-
-
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-
-
-
-
-
-
-
3
-
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-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
693689
Nurmohamed
Crystal structure of Escherich ...
Escherichia coli
J. Mol. Biol.
389
17-33
2009
-
-
-
1
-
-
-
-
-
-
-
-
-
5
-
-
-
-
-
-
-
-
2
-
1
-
-
-
-
-
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-
-
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-
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1
-
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-
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-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
694247
Schuck
RNase E autoregulates its synt ...
Escherichia coli
Mol. Microbiol.
72
470-478
2009
-
-
-
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
2
-
1
-
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-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
694921
Singh
Regulation of ribonuclease E a ...
Escherichia coli
Proc. Natl. Acad. Sci. USA
106
864-869
2009
-
-
1
-
-
-
1
-
1
-
-
-
-
4
-
-
1
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
706936
Zhang
Post-transcriptional regulatio ...
Rhizobium leguminosarum bv. viciae, Rhizobium leguminosarum bv. viciae 8401/pRL1JI
Acta Biochim. Biophys. Sin. (Shanghai)
41
719-730
2009
1
-
1
-
-
-
1
-
-
-
1
-
-
7
-
-
1
-
-
-
-
-
2
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
1
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
707561
Erce
Identification and functional ...
Escherichia coli, Photobacterium angustum S14
Biochim. Biophys. Acta
1794
1107-1114
2009
-
-
2
-
-
-
-
-
-
-
1
-
-
6
-
-
-
-
-
-
-
-
4
-
2
-
-
-
-
-
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-
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1
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-
-
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-
-
4
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
708928
Zhou
Transcriptional regulation of ...
Escherichia coli
J. Bacteriol.
191
6665-6674
2009
-
-
-
-
-
-
1
-
-
-
-
-
-
5
-
-
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-
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-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
710335
Nishio
Arginine-rich RNA binding doma ...
Escherichia coli
Plasmid
62
83-87
2009
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
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-
1
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-
-
3
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
684890
Lombo
RNA processing in Aquifex aeol ...
Aquifex aeolicus
Biochem. Biophys. Res. Commun.
366
457-463
2008
-
-
-
-
-
-
-
-
-
1
-
3
-
1
-
-
-
-
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-
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-
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-
-
-
3
-
1
-
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-
1
-
-
-
-
-
-
-
-
-
685269
Ko
Dual function of RNase E for c ...
Escherichia coli
Biochemistry
47
762-770
2008
-
-
-
-
-
-
-
-
-
1
-
1
-
3
-
-
-
-
-
-
-
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2
-
1
1
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-
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2
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
686963
Shin
Identification of amino acid r ...
Escherichia coli
Genetics
179
1871-1879
2008
-
-
-
-
3
-
-
-
-
-
-
3
-
6
-
-
-
1
-
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3
-
1
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3
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-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
689258
Perwez
Intragenic suppressors of temp ...
Escherichia coli, Escherichia coli MG1693
Nucleic Acids Res.
36
5306-5318
2008
-
-
-
-
4
-
-
-
-
-
-
-
-
9
-
-
-
-
-
-
-
-
2
-
1
-
-
-
-
-
-
-
-
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4
-
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-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
690026
Schein
The RNase E/G-type endoribonuc ...
Arabidopsis thaliana
RNA
14
1057-1068
2008
-
-
1
-
-
-
2
-
3
1
2
2
-
13
-
-
-
-
-
1
-
-
5
2
2
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
2
-
-
3
1
2
2
-
-
-
-
-
1
-
-
5
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
690031
Coros
A mutant screen reveals RNase ...
Escherichia coli
RNA
14
2634-2644
2008
-
-
-
-
1
-
-
-
-
-
-
-
-
5
-
-
-
-
-
-
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1
-
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-
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-
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-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
690089
Koslover
The crystal structure of the E ...
Escherichia coli
Structure
16
1238-1244
2008
-
-
-
2
-
-
-
-
-
3
-
1
-
4
-
-
-
-
-
-
-
-
6
3
1
-
-
-
-
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-
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-
1
-
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-
-
-
-
-
6
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
692383
Spinelli
Regulation of magnesium homeos ...
Salmonella enterica
FEMS Microbiol. Lett.
280
226-234
2008
-
-
1
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
-
-
-
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-
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-
-
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-
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-
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-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
692391
Yeom
Inhibitory effects of RraA and ...
Streptomyces coelicolor
FEMS Microbiol. Lett.
285
10-15
2008
-
-
1
-
-
-
2
-
-
-
-
-
-
5
-
-
-
-
-
-
-
-
2
-
2
-
-
-
-
-
-
-
-
-
-
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-
-
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-
-
-
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-
2
-
-
-
-
-
-
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-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
694008
Mackie
Preparation of the Escherichia ...
Escherichia coli, Escherichia coli GM402 BL21(DE3)
Methods Enzymol.
447
199-213
2008
-
-
-
-
-
-
-
-
-
-
-
-
-
6
-
-
1
-
1
-
-
-
4
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
694009
Kime
Identifying and characterizing ...
Escherichia coli
Methods Enzymol.
447
215-241
2008
-
-
-
-
-
-
-
1
-
-
-
-
-
5
-
-
1
-
-
-
-
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-
-
2
-
-
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-
1
-
-
-
-
-
-
-
-
-
-
694239
Hammarloef
Mutants of the RNA-processing ...
Salmonella enterica
Mol. Microbiol.
70
1194-1209
2008
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
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1
-
-
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-
-
-
-
-
-
-
-
-
-
-
694243
Khemici
The RNase E of Escherichia col ...
Escherichia coli, Escherichia coli KSL2000
Mol. Microbiol.
70
799-813
2008
-
-
1
-
1
-
-
-
1
-
1
-
-
4
-
-
1
-
1
-
-
-
4
1
1
-
-
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1
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1
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1
-
-
-
4
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
725381
Beloglazova
A novel family of sequence-spe ...
Saccharolobus solfataricus, Saccharolobus solfataricus P2
J. Biol. Chem.
283
20361-20371
2008
-
-
1
1
15
-
-
-
-
2
2
-
-
4
-
-
1
-
-
-
-
-
2
1
1
-
-
-
-
1
1
-
-
-
-
-
-
-
1
-
1
15
-
-
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2
-
-
-
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1
-
-
-
-
2
1
-
-
-
-
1
1
-
-
-
1
1
-
-
-
685655
Takada
RNase E is required for induct ...
Escherichia coli
Biosci. Biotechnol. Biochem.
71
158-164
2007
-
-
1
-
1
-
-
-
-
-
-
1
-
4
-
-
-
-
-
-
-
-
1
-
1
-
-
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-
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-
-
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-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
687379
Hankins
Role of RNA structure and susc ...
Escherichia coli
J. Bacteriol.
189
4353-4358
2007
-
-
-
-
1
-
-
-
1
1
-
1
-
1
-
-
-
-
-
-
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-
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1
-
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1
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-
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-
-
2
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
688345
Chandran
Recognition and cooperation be ...
Escherichia coli
J. Mol. Biol.
367
113-132
2007
-
-
-
-
1
-
-
-
1
1
-
1
-
3
-
-
-
-
-
-
-
-
2
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
1
-
1
-
-
-
-
-
-
-
-
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
689046
Davis
RNase E-dependent processing s ...
Vibrio cholerae serotype O1
Mol. Microbiol.
65
373-385
2007
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
4
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
689760
Taghbalout
RNase E and the other constitu ...
Escherichia coli
Proc. Natl. Acad. Sci. USA
104
1667-1672
2007
-
-
1
-
1
-
-
-
2
-
-
1
-
3
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
752028
Taghbalout
RNaseE and the other constitu ...
Escherichia coli, Escherichia coli K12 PB103
Proc. Natl. Acad. Sci. USA
104
1667-1672
2007
-
-
-
-
-
-
-
-
1
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
687518
Caruthers
Retention of core catalytic fu ...
Escherichia coli, Haemophilus influenzae
J. Biol. Chem.
281
27046-27051
2006
-
-
2
-
2
-
-
-
-
2
-
-
-
8
-
-
2
-
-
-
-
-
2
-
2
2
-
2
-
2
-
-
-
-
-
-
-
-
2
-
-
2
-
-
-
-
-
-
2
-
-
-
-
-
2
-
-
-
-
2
-
2
-
2
-
2
-
-
-
-
-
-
-
-
-
667401
Kaberdin
Characterization of Aquifex ae ...
Aquifex aeolicus
Biochem. Biophys. Res. Commun.
327
382-392
2005
-
-
2
-
-
-
-
-
-
1
-
2
-
8
-
-
2
-
-
-
-
-
10
-
3
2
1
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
1
-
2
-
-
-
2
-
-
-
-
10
-
2
1
-
-
1
-
-
-
-
-
-
-
-
-
669862
Soederbom
RNase E cleavage in the 5' lea ...
Escherichia coli
J. Mol. Biol.
352
22-27
2005
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
2
-
1
-
-
-
-
-
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-
-
-
-
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-
-
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-
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-
-
-
-
-
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1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
670376
Callaghan
Structure of Escherichia coli ...
Escherichia coli
Nature
437
1187-1191
2005
-
-
1
1
7
-
-
-
1
3
1
2
-
5
-
-
1
1
-
-
-
-
6
2
2
2
-
-
-
2
-
-
-
-
-
-
-
-
1
-
1
7
-
-
-
-
-
1
3
1
2
-
-
-
1
-
-
-
-
6
2
2
-
-
-
2
-
-
-
-
-
-
-
-
-
670428
Afonyushkin
Both RNase E and RNase III con ...
Escherichia coli
Nucleic Acids Res.
33
1678-1689
2005
2
-
-
-
-
-
-
-
-
3
-
2
-
1
-
-
-
-
-
-
-
-
4
-
1
1
-
-
-
1
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
3
-
2
-
-
-
-
-
-
-
-
4
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
685062
Callaghan
Zn-link: a metal-sharing inter ...
Escherichia coli
Biochemistry
44
4667-4675
2005
-
-
1
-
2
-
1
-
-
2
4
1
-
3
-
-
1
-
-
-
-
-
1
3
1
1
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
2
-
-
1
-
-
-
2
4
1
-
-
-
1
-
-
-
-
1
3
1
-
-
-
1
-
-
-
-
-
-
-
-
-
667337
Hambraeus
Escherichia coli RNase E and R ...
Escherichia coli
Arch. Microbiol.
181
137-143
2004
-
-
-
-
-
-
-
-
-
-
-
1
-
7
-
-
-
-
-
-
1
-
2
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
669144
Kim
Kinetic analysis of precursor ...
Escherichia coli, Escherichia coli JM109
J. Biochem.
136
693-699
2004
-
-
1
-
-
-
-
7
-
-
-
-
-
33
-
-
1
-
-
-
1
-
12
-
1
1
-
-
7
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
7
-
-
-
-
-
-
-
1
-
-
1
-
12
-
1
-
-
7
1
-
-
-
-
-
-
-
-
-
669834
Schubert
Structural characterization of ...
Escherichia coli
J. Mol. Biol.
341
37-54
2004
-
-
1
1
1
-
-
-
-
-
-
-
-
3
-
-
1
-
-
-
-
-
1
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
1
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
670667
Jiang
Catalytic activation of multim ...
Escherichia coli
Proc. Natl. Acad. Sci. USA
101
9211-9216
2004
1
-
1
-
-
-
-
3
-
2
-
-
-
3
-
-
1
-
-
-
1
-
5
1
1
1
-
-
2
1
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
3
-
2
-
-
-
-
-
1
-
-
1
-
5
1
1
-
-
2
1
-
-
-
-
-
-
-
-
-
667576
Callaghan
Quaternary structure and catal ...
Escherichia coli
Biochemistry
42
13848-13855
2003
-
-
1
1
-
-
-
-
-
1
1
-
-
6
-
-
1
-
-
-
-
-
2
1
2
1
-
-
-
1
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
1
1
-
-
-
-
1
-
-
-
-
2
1
1
-
-
-
1
-
-
-
-
-
-
-
-
-
669202
Redko
Determination of the catalytic ...
Escherichia coli
J. Biol. Chem.
278
44001-44008
2003
-
-
1
-
-
-
-
1
-
2
-
1
-
4
-
-
1
-
-
-
1
-
3
-
1
-
-
-
-
1
1
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
1
-
2
-
1
-
-
-
1
-
-
1
-
3
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
670424
Kaberdin
Probing the substrate specific ...
Escherichia coli
Nucleic Acids Res.
31
4710-4716
2003
-
1
1
-
-
-
-
-
-
-
-
-
-
4
-
-
1
-
-
-
1
-
5
1
1
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
5
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
667376
Klein
RNase E is involved in 5'-end ...
Rhizobium leguminosarum, Rhodobacter capsulatus, Rhodobacter capsulatus DSM 938
Biochem. Biophys. Res. Commun.
299
780-786
2002
-
-
-
-
-
-
-
-
-
1
-
3
-
5
-
-
-
-
-
-
-
-
9
-
2
2
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
3
-
-
-
-
-
-
-
-
9
-
2
-
-
-
2
-
-
-
-
-
-
-
-
-
668734
Ow
Initiation of tRNA maturation ...
Escherichia coli
Genes Dev.
16
1102-1115
2002
-
-
1
-
1
-
-
1
-
-
-
6
-
5
-
-
-
-
-
-
1
-
7
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
1
-
-
-
6
-
-
-
-
-
-
1
-
7
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
670301
Diwa
Two distinct regions on the su ...
Escherichia coli
Mol. Microbiol.
46
959-969
2002
-
-
1
-
16
-
-
-
-
-
-
1
-
3
-
-
1
-
1
-
1
-
2
1
2
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
16
-
-
-
-
-
-
-
-
1
-
-
-
1
1
-
1
-
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
670721
Feng
The catalytic domain of RNase ...
Escherichia coli
Proc. Natl. Acad. Sci. USA
99
14746-14751
2002
1
-
1
-
-
-
1
-
-
2
-
-
-
3
-
-
1
-
-
-
-
-
4
1
1
1
-
-
-
1
-
-
-
-
-
-
1
-
1
-
-
-
-
-
1
-
-
-
2
-
-
-
-
-
1
-
-
-
-
4
1
1
-
-
-
1
-
-
-
-
-
-
-
-
-
670877
Li
RNase E plays an essential rol ...
Escherichia coli K-12, Escherichia coli K-12 CA244
RNA
8
97-109
2002
-
-
-
-
1
-
-
-
-
1
-
7
-
6
-
-
-
-
-
-
-
-
13
-
1
1
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
7
-
-
-
-
-
-
-
-
13
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
670423
Walsh
Cleavage of poly(A) tails on t ...
Escherichia coli, Escherichia coli BRL2288
Nucleic Acids Res.
29
1864-1871
2001
-
-
1
-
-
-
1
-
1
1
-
-
-
5
-
-
1
-
-
-
-
-
2
1
2
1
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
1
1
-
-
-
-
-
1
-
-
-
-
2
1
1
-
-
-
1
-
-
-
-
-
-
-
-
-
669074
Jiang
Regions of RNase E important f ...
Synechocystis sp., Escherichia coli K-12
J. Bacteriol.
182
2468-2475
2000
1
-
2
-
1
-
-
-
-
4
-
1
-
6
-
-
2
-
-
-
2
-
9
2
3
2
-
-
-
2
-
-
-
-
-
-
1
-
2
-
-
1
-
-
-
-
-
-
4
-
1
-
-
-
2
-
-
2
-
9
2
2
-
-
-
2
-
-
-
-
-
-
-
-
-
668399
Li
RNase G (CafA protein) and RNa ...
Escherichia coli
EMBO J.
18
2878-2885
1999
-
-
-
-
1
-
-
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-
1
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2
-
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2
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-
-
669073
Heck
RNase E enzymes from Rhodobact ...
Escherichia coli, Rhodobacter capsulatus, Escherichia coli N3433
J. Bacteriol.
181
7621-7625
1999
-
-
-
-
2
-
-
-
-
-
-
3
-
11
-
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6
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6
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-
668733
Vanzo
Ribonuclease E organizes the p ...
Escherichia coli
Genes Dev.
12
2770-2781
1998
-
-
1
-
1
-
-
-
1
-
-
1
-
4
-
-
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1
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670370
Mackie
Ribonuclease E is a 5'-end-dep ...
Escherichia coli, Escherichia coli CF 881
Nature
395
720-723
1998
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4
-
4
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1
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10
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10
1
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-
669186
Mackie
Modulation of the activity of ...
Escherichia coli
J. Biol. Chem.
272
609-616
1997
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
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8
-
2
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-
-
8
-
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-
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-
-
-
670298
Cohen
RNase E: still a wonderfully m ...
Escherichia coli, Rhodobacter capsulatus, Streptomyces lividans
Mol. Microbiol.
23
1099-1106
1997
-
-
1
-
1
-
-
-
2
-
2
1
-
5
-
-
-
-
-
-
-
-
6
2
7
-
-
-
-
-
-
-
-
-
-
-
-
-
1
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-
1
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-
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2
-
2
1
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-
-
6
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
669185
Kaberdin
RNase E cleaves at multiple si ...
Escherichia coli K-12
J. Biol. Chem.
271
13103-13109
1996
-
-
-
-
-
-
-
-
-
1
-
-
-
3
-
-
1
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-
1
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-
1
-
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-
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-
670326
Mudd
Escherichia coli endoribonucle ...
Escherichia coli
Mol. Microbiol.
9
557-568
1993
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-
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1
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3
-
1
1
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4
1
1
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1
-
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-
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-
-
-
670712
Cormack
RNase E activity is conferred ...
Escherichia coli, Escherichia coli 18-11BP
Proc. Natl. Acad. Sci. USA
90
9006-9010
1993
-
-
1
-
-
-
-
-
-
1
1
4
-
4
-
-
1
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11
1
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1
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4
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-
11
1
1
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-
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-
668738
Ehretsmann
Specificity of Escherichia col ...
Escherichia coli
Genes Dev.
6
149-159
1992
-
-
-
-
-
-
1
-
-
1
-
1
-
7
-
-
1
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-
-
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2
-
2
1
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1
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-
1
-
-
-
-
-
-
-
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-
669070
Patel
RNase E-dependent cleavages in ...
Escherichia coli
J. Bacteriol.
174
3541-3548
1992
-
-
-
-
-
-
-
-
-
-
-
1
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2
-
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