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Literature summary for 3.1.26.12 extracted from

  • Taghbalout, A.; Rothfield, L.
    RNase E and the other constituents of the RNA degradosome are components of the bacterial cytoskeleton (2007), Proc. Natl. Acad. Sci. USA, 104, 1667-1672.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.26.12

Cloned(Commentary)

Cloned (Comment) Organism
gene rne, expression of wild-type and mutant enzymes in Escherichia coli and in the Saccharomyces cerevisiae two-hybrid system Escherichia coli

Protein Variants

Protein Variants Comment Organism
additional information the constructed rne mutant strains AT8, i.e. Prne-rne1-417, and AT14, i.e. Prne-rne1-659, show loss of the helical protein organization and reduced activity, AT8 cells grow slowly and show a defect in cell division as shown by a mixed population ranging from normal-length cells to long filaments, AT8 cells exhibit a chromosome segregation defect, phenotypes, overview Escherichia coli

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoskeleton RNase E and the other constituents of the RNA degradosome are components of the bacterial cytoskeleton, degradosome components, i.e. RNase E, helicase B, polynucleotide hosphorylase, and enolase, are organized as helical filamentous structures that coil around the length of the cell. Formation of the RNaseE cytoskeletal-like structure requires an internal domain of the protein that does not include the domains required for any of its known interactions or the minimal domain required for endonuclease activity, but is independent of MreB and MinD cytoskeletal structures, mechanism of assembly, overview Escherichia coli 5856
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additional information the enzyme is the main part of the RNA degradosome Escherichia coli
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Escherichia coli RNaseE, as the main component of the RNA degradosome of Escherichia coli, plays an essential role in RNA processing and decay ?
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 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
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 gene rne
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information RNaseE, as the main component of the RNA degradosome of Escherichia coli, plays an essential role in RNA processing and decay Escherichia coli ?
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 ?

Synonyms

Synonyms Comment Organism
RNase E
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 Escherichia coli