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Literature summary for 3.1.21.5 extracted from

  • Meisel, A.; Bickle, T.A.; Kruger, T.A.; Kruger, D.H.; Schroeder, C.
    Type III restriction enzymes need two inversely oriented recognition sites for DNA cleavage (1992), Nature, 355, 467-469.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Escherichia coli
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EcoP15
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
DNA + H2O EcoP15 restriction is a very fast reaction that requires two unmodified recognition sites in inverted orientation. EcoP15 methylation is a slower reaction and is independent of the orientation of the sites Escherichia coli specific double-stranded DNA fragments with terminal 5'-phosphate
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