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Literature summary for 3.1.21.4 extracted from

  • Zhao, G.; Li, J.; Tong, Z.; Zhao, B.; Mu, R.; Guan, Y.
    Enzymatic cleavage of type II restriction endonucleases on the 2-O-methyl nucleotide and phosphorothioate substituted DNA (2013), PLoS ONE, 8, e79415.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
additional information a substitution of DNA with 2'-O-methyl nucleotide and phosphorothioate shows inhibitory effect on enzyme activity Escherichia coli
additional information a substitution of DNA with 2'-O-methyl nucleotide and phosphorothioate shows inhibitory effect on enzyme activity Providencia stuartii
additional information a substitution of DNA with 2'-O-methyl nucleotide and phosphorothioate shows inhibitory effect on enzyme activity Sphaerotilus natans
additional information a substitution of DNA with 2'-O-methyl nucleotide and phosphorothioate shows inhibitory effect on enzyme activity Streptomyces phaeochromogenes
additional information a substitution of DNA with 2'-O-methyl nucleotide and phosphorothioate shows inhibitory effect on enzyme activity Xanthomonas vasicola

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
double-stranded DNA + H2O Escherichia coli
-
double-stranded DNA fragments with terminal 5'-phosphates
-
?
double-stranded DNA + H2O Streptomyces phaeochromogenes
-
double-stranded DNA fragments with terminal 5'-phosphates
-
?
double-stranded DNA + H2O Providencia stuartii
-
double-stranded DNA fragments with terminal 5'-phosphates
-
?
double-stranded DNA + H2O Xanthomonas vasicola
-
double-stranded DNA fragments with terminal 5'-phosphates
-
?
double-stranded DNA + H2O Sphaerotilus natans
-
double-stranded DNA fragments with terminal 5'-phosphates
-
?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-
Providencia stuartii
-
-
-
Sphaerotilus natans
-
-
-
Streptomyces phaeochromogenes
-
-
-
Xanthomonas vasicola
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
double-stranded DNA + H2O
-
Escherichia coli double-stranded DNA fragments with terminal 5'-phosphates
-
?
double-stranded DNA + H2O
-
Streptomyces phaeochromogenes double-stranded DNA fragments with terminal 5'-phosphates
-
?
double-stranded DNA + H2O
-
Providencia stuartii double-stranded DNA fragments with terminal 5'-phosphates
-
?
double-stranded DNA + H2O
-
Xanthomonas vasicola double-stranded DNA fragments with terminal 5'-phosphates
-
?
double-stranded DNA + H2O
-
Sphaerotilus natans double-stranded DNA fragments with terminal 5'-phosphates
-
?

Synonyms

Synonyms Comment Organism
EcoRV
-
Escherichia coli
PstI
-
Providencia stuartii
SpeI
-
Sphaerotilus natans
SphI
-
Streptomyces phaeochromogenes
type II REase
-
Escherichia coli
type II REase
-
Streptomyces phaeochromogenes
type II REase
-
Providencia stuartii
type II REase
-
Xanthomonas vasicola
type II REase
-
Sphaerotilus natans
type II restriction endonuclease
-
Escherichia coli
type II restriction endonuclease
-
Streptomyces phaeochromogenes
type II restriction endonuclease
-
Providencia stuartii
type II restriction endonuclease
-
Xanthomonas vasicola
type II restriction endonuclease
-
Sphaerotilus natans
XhoI
-
Xanthomonas vasicola