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Literature summary for 3.1.21.3 extracted from

  • Taylor, I.; Watts, D.; Kneale, G.
    Substrate recognition and selectivity in the type IC DNA modification methylase M.EcoR124I (1993), Nucleic Acids Res., 2, 4929-4935.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Escherichia coli
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enzyme EcoR124I
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
duplex DNA + ATP the modification methylase binds sequence specifically to DNA and protects a 25bp fragment containing its cognate recognition sequence from digestion by exonuclease III, specific adenine on each strand of DNA is the site of methylation Escherichia coli double-stranded DNA fragments with terminal 5'-phosphate + ADP + inorganic phosphate
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Synonyms

Synonyms Comment Organism
EcoR124I
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Escherichia coli