Literature summary for 3.1.21.2 extracted from

Zhang, W.; Xu, Y.; Yan, M.; Li, S.; Wang, H.; Yang, H.; Zhou, W.; Rao, Z.
Crystal structure of the apurinic/apyrimidinic endonuclease IV from Mycobacterium tuberculosis (2018), Biochem. Biophys. Res. Commun., 498, 111-118 .

Search for more literature for 3.1.21.2

Application

Application	Comment	Organism
pharmacology	this enzyme is absent from mammalian cells, making it an attractive target for anti-tuberculosis drug development	Mycobacterium tuberculosis

Crystallization (Commentary)

Crystallization (Comment)	Organism
sitting-drop vapor-diffusion method at 18°C, the structure of the recombinant endonuclease IV is determined at 1.18 A resolution	Mycobacterium tuberculosis

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Zn2+	three zinc ions are identified at the active site	Mycobacterium tuberculosis

Organism

Organism	UniProt	Comment	Textmining
Mycobacterium tuberculosis	P9WQ13	-	-
Mycobacterium tuberculosis H37Rv	P9WQ13	-	-

Synonyms

Synonyms	Comment	Organism
endonuclease IV	-	Mycobacterium tuberculosis
MtbEndo IV	-	Mycobacterium tuberculosis

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Release 2023.1 (January 2023)