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Literature summary for 3.1.21.1 extracted from

  • Zhao, W.; Lam, J.C.; Chiuman, W.; Brook, M.A.; Li, Y.
    Enzymatic cleavage of nucleic acids on gold nanoparticles: a generic platform for facile colorimetric biosensors (2008), Small, 4, 810-816.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
2-(4-amidinophenyl)-6-indolecarbamidine significantly inhibits DNase I activity Homo sapiens
additional information efficiency of cleavage of DNA duplex on gold nanoparticles by DNase I is about 82% whereas the cleavage efficiency in solution phase at the same conditions is nearly 100%. Cleavage efficiencies using Pb2+-mediated DNA enzyme on gold nanoparticles and in solution phase are about 55% and 95%, respectively Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
DNA + H2O complementary DNA S2 allowed to hybridize with S1 forms DNA duplexes (the substrate for DNase I) on gold nanoparticles Homo sapiens 5'-phosphooligonucleotides + ?
-
?

Synonyms

Synonyms Comment Organism
DNase I
-
Homo sapiens