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BRENDA support

Literature summary for 3.1.2.6 extracted from

  • Antognelli, C.; Baldracchini, F.; Talesa, V.N.; Costantini, E.; Zucchi, A.; Mearini, E.
    Overexpression of glyoxalase system enzymes in human kidney tumor (2006), Cancer J., 12, 222-228.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
Homo sapiens
-
kidney tumor cell transcription of glyoxalase II is about threefold increased in cancerous tissue comared to noncancerous tissue. Glyoxalase II activity is significantly lower in pathological tissues than in normal ones Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-D-lactoylglutathione + H2O
-
Homo sapiens D-lactate + glutathione
-
?

Synonyms

Synonyms Comment Organism
glyoxalase II
-
Homo sapiens