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Literature summary for 3.1.2.6 extracted from

  • Marasinghe, G.P.K.; Sander, I.M.; Bennett, B.; Periyannan, G.; Yang, K.W.; Makaroff, C.A.; Crowder, M.W.
    Structural Studies on a mitochondrial glyoxalase II (2005), J. Biol. Chem., 280, 40668-40675.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.2.6

Cloned(Commentary)

Cloned (Comment) Organism
-
 Arabidopsis thaliana

Crystallization (Commentary)

Crystallization (Comment) Organism
recombinant enzyme, and comparison with human enzyme Arabidopsis thaliana

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.391
-
 S-Lactoylglutathione 25°C, pH 7.2 Arabidopsis thaliana

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion isoform glyoxalase II Arabidopsis thaliana 5739
-

Metals/Ions

Metals/Ions Comment Organism Structure
Iron 1.04 mol per mol of enzyme, contains a predominant Fe(III)Zn(II) center and an anti-ferromagnetically coupled Fe(III)Fe(II) center Arabidopsis thaliana
additional information not: manganese Arabidopsis thaliana
Zinc 1.31 mol per mol of enzmye Arabidopsis thaliana

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana Q9SID3
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information no substrate: S-formylglutathione Arabidopsis thaliana ?
-
 ?
S-acetoacetylglutathione + H2O hydrolysis at about half the rate of S-lactoylglutathione Arabidopsis thaliana acetoacetate + glutathione
-
 ?
S-acetylglutathione + H2O hydrolysis about 10fold lower than of S-lactoylglutathione Arabidopsis thaliana acetate + glutathione
-
 ?
S-glycolylglutathione + H2O hydrolysis at about half the rate of S-lactoylglutathione Arabidopsis thaliana ? + glutathione
-
 ?
S-lactonylglutathione + H2O hydrolysis about 10fold lower than of S-lactoylglutathione Arabidopsis thaliana ? + glutathione
-
 ?
S-lactoylglutathione + H2O preferred substrae Arabidopsis thaliana D-lactate + glutathione
-
 ?
S-mandeloylglutathione + H2O hydrolysis about 10fold lower than of S-lactoylglutathione Arabidopsis thaliana mandelic acid + glutathione
-
 ?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
129
-
 S-Lactoylglutathione
-
 Arabidopsis thaliana