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Literature summary for 3.1.2.6 extracted from
- Glyoxalase II from mouse liver (1982), Methods Enzymol., 90, 547-551.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| glutathione | a combination of methylglyoxal and glutathione has a greater than additive inhibitory activity | Mus musculus |  |
| methylglyoxal | - |
Mus musculus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.27 | - |
S-D-lactoylglutathione | - |
Mus musculus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Mus musculus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Mus musculus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 614.7 | - |
- |
Mus musculus |
Storage Stability
| Storage Stability | Organism |
|---|---|
| -30°C, 1 mM S-octylglutathione, no significant loss of activity for at least 6 months | Mus musculus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| lactoylglutathione + H2O | - |
Mus musculus | D-lactate + glutathione | - |
? | |
| S-D-lactoylglutathione + H2O | - |
Mus musculus | D-lactate + glutathione | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | - |
Mus musculus |
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Release 2023.1 (January 2023)
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