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Literature summary for 3.1.2.6 extracted from
- Glyoxalase II: molecular characteristics, kinetic and mechanism (1993), Biochem. Soc. Trans., 21, 522-527.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 2,4,6-Trinitrobenzenesulfonate | N-acetyl-S-(p-bromobenzyl)glutathione protects | Homo sapiens |  |
| 2,4,6-Trinitrobenzenesulfonate | N-acetyl-S-(p-bromobenzyl)glutathione protects | Rattus norvegicus | |
| diethyldicarbonate | pH 6 | Rattus norvegicus | |
| N-acetyl-S-(p-bromobenzyl)glutathione | competitive | Homo sapiens | |
| N-acetyl-S-(p-bromobenzyl)glutathione | competitive | Rattus norvegicus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
| Rattus norvegicus | - |
- |
- |
Reaction
| Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|
| S-(2-hydroxyacyl)glutathione + H2O = glutathione + a 2-hydroxy carboxylate | mechanism | Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Homo sapiens | - |
| brain | - |
Rattus norvegicus | - |
| erythrocyte | - |
Homo sapiens | - |
| erythrocyte | - |
Rattus norvegicus | - |
| liver | - |
Homo sapiens | - |
| liver | - |
Rattus norvegicus | - |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | turnover-numver is pH-independent in the range pH 6-9.3 | Rattus norvegicus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 6.8 | 7.5 | - |
Homo sapiens |
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