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Literature summary for 3.1.2.4 extracted from

  • Pan, Y.; Yang, J.; Gong, Y.; Li, X.; Hu, H.
    3-Hydroxyisobutyryl-CoA hydrolase involved in isoleucine catabolism regulates triacylglycerol accumulation in Phaeodactylum tricornutum (2017), Philos. Trans. R. Soc. Lond. B Biol. Sci., 372, 20160409 .
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(S)-3-hydroxyisobutyryl-CoA + H2O Phaeodactylum tricornutum
-
CoA + (S)-3-hydroxyisobutyrate
-
ir
3-hydroxypropionyl-CoA + H2O Phaeodactylum tricornutum
-
CoA + 3-hydroxypropionate
-
ir

Organism

Organism UniProt Comment Textmining
Phaeodactylum tricornutum
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-3-hydroxyisobutyryl-CoA + H2O
-
Phaeodactylum tricornutum CoA + (S)-3-hydroxyisobutyrate
-
ir
3-hydroxypropionyl-CoA + H2O
-
Phaeodactylum tricornutum CoA + 3-hydroxypropionate
-
ir

Synonyms

Synonyms Comment Organism
HIBCH
-
Phaeodactylum tricornutum

General Information

General Information Comment Organism
metabolism enzyme overexpression accelerates L-Ile degradation and triacylglycerol accumulation and results in a lowered L-Ile content Phaeodactylum tricornutum