Cloned (Comment) | Organism |
---|---|
expressed in COS-7 and HEK-293 cells | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
C6S | the activity of the non-palmitoylatable mutant significantly surpasses that of the wild type enzyme by more than 42% in the cell lysate and 25% in the cell medium | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
endoplasmic reticulum | - |
Homo sapiens | 5783 | - |
Golgi apparatus | - |
Homo sapiens | 5794 | - |
lysosome | - |
Homo sapiens | 5764 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P50897 | - |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
palmitoylation | the enzyme is palmitoylated at Cys-6 by DHHC3 and DHHC7 | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-methylumbelliferyl 6-S-palmitoyl-6-thio-beta-D-glucoside + H2O | - |
Homo sapiens | palmitate + 4-methylumbelliferyl 6-thio-beta-D-glucoside | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 35000, SDS-PAGE | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
palmitoyl-protein thioesterase 1 | - |
Homo sapiens |
PPT1 | - |
Homo sapiens |