BRENDA - Enzyme Database show
show all sequences of 3.1.2.22

A mutation in canine PPT1 causes early onset neuronal ceroid lipofuscinosis in a Dachshund

Sanders, D.N.; Farias, F.H.; Johnson, G.S.; Chiang, V.; Cook, J.R.; OBrien, D.P.; Hofmann, S.L.; Lu, J.Y.; Katz, M.L.; Mol. Genet. Metab. 100, 349-356 (2010)

Data extracted from this reference:

Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Canis lupus familiaris
Q5JZR0
Miniature Dachshund
-
Specific Activity [micromol/min/mg]
Specific Activity Minimum [Ámol/min/mg]
Specific Activity Maximum [Ámol/min/mg]
Commentary
Organism
0.0055
-
substrate 4-methylumbelliferyl 6-deoxy-6-thiopalmitoyl-beta-D-glucopyranoside, cerebral cortex gray matter lysate, pH not specified in the publication, temperature not specified in the publication
Canis lupus familiaris
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4-methylumbelliferyl 6-deoxy-6-thiopalmitoyl-beta-D-glucopyranoside + H2O
-
716234
Canis lupus familiaris
4-methylumbelliferyl 6-deoxy-6-thio-beta-D-glucopyranoside + palmitate
-
-
-
?
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [Ámol/min/mg]
Specific Activity Maximum [Ámol/min/mg]
Commentary
Organism
0.0055
-
substrate 4-methylumbelliferyl 6-deoxy-6-thiopalmitoyl-beta-D-glucopyranoside, cerebral cortex gray matter lysate, pH not specified in the publication, temperature not specified in the publication
Canis lupus familiaris
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4-methylumbelliferyl 6-deoxy-6-thiopalmitoyl-beta-D-glucopyranoside + H2O
-
716234
Canis lupus familiaris
4-methylumbelliferyl 6-deoxy-6-thio-beta-D-glucopyranoside + palmitate
-
-
-
?
General Information
General Information
Commentary
Organism
malfunction
neuronal ceroid lipofuscinoses-like signs caused by single nucleotide insertion in exon 8 (homozygous)
Canis lupus familiaris
General Information (protein specific)
General Information
Commentary
Organism
malfunction
neuronal ceroid lipofuscinoses-like signs caused by single nucleotide insertion in exon 8 (homozygous)
Canis lupus familiaris
Other publictions for EC 3.1.2.22
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [░C]
Temperature Range [░C]
Temperature Stability [░C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [░C] (protein specific)
Temperature Range [░C] (protein specific)
Temperature Stability [░C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
729768
Aby
Mutations in palmitoyl-protein ...
Drosophila melanogaster
Fly
7
267-279
2014
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730430
Liu
Palmitoyl-protein thioesterase ...
Rattus norvegicus
Mol. Reprod. Dev.
81
55-65
2014
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1
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730399
Hu
Intravenous high-dose enzyme r ...
Mus musculus
Mol. Genet. Metab.
107
213-221
2012
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1
1
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709975
Lu
Human recombinant palmitoyl-pr ...
Homo sapiens
Mol. Genet. Metab.
99
374-378
2010
-
1
1
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4
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1
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-
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1
1
-
-
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710070
Saja
Identifying cellular pathways ...
Drosophila melanogaster, Drosophila sp. (in: Insecta)
Neurobiol. Dis.
40
135-145
2010
1
-
2
-
4
-
1
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2
2
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716234
Sanders
A mutation in canine PPT1 caus ...
Canis lupus familiaris
Mol. Genet. Metab.
100
349-356
2010
-
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1
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1
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1
1
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-
716683
Chu-LaGraff
The Batten disease Palmitoyl P ...
Drosophila melanogaster
PLoS ONE
5
e14402
2010
-
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1
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1
1
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707548
Hirano
Thioesterase activity and subc ...
Homo sapiens
Biochim. Biophys. Acta
1791
797-805
2009
-
-
1
-
1
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2
2
1
1
1
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2
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1
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2
1
2
1
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1
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2
1
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1
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1
2
1
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1
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-
707557
Tardy
Palmitoyl protein thioesterase ...
Homo sapiens, Mus musculus
Biochim. Biophys. Acta
1793
1250-1258
2009
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1
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2
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2
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-
-
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4
4
-
-
-
708433
Macauley
Cerebellar pathology and motor ...
Mus musculus
Exp. Neurol.
217
124-135
2009
-
-
-
-
-
-
-
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2
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2
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1
1
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-
692414
Bannan
The Drosophila protein palmito ...
Drosophila melanogaster
Fly
2
198-214
2008
-
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1
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1
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693353
Kim
Palmitoyl protein thioesterase ...
Homo sapiens, Mus musculus
J. Clin. Invest.
118
3075-3086
2008
-
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1
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6
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4
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4
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1
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6
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4
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707922
Takano
Infantile neuronal ceroid lipo ...
Homo sapiens
Brain Dev.
30
370-373
2008
-
1
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1
1
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-
678930
Lyly
Glycosylation, transport, and ...
Homo sapiens
BMC Cell Biol.
8
22
2007
-
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4
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1
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1
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1
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1
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-
680026
Buff
Genetic modifiers of Drosophil ...
Drosophila sp. (in: Insecta)
Genetics
176
209-220
2007
-
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664616
Kohan
Palmitoyl protein thioesterase ...
Homo sapiens
Clin. Biochem.
38
492-494
2005
-
1
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665136
Zhang
Palmitoyl-protein thioesterase ...
Mus musculus
Hum. Mol. Genet.
15
337-346
2005
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666135
Porter
Identification and characteriz ...
Caenorhabditis elegans
J. Neurosci. Res.
79
836-848
2005
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651030
Cho
pdf1, a palmitoyl protein thio ...
Schizosaccharomyces pombe
Eukaryot. Cell
3
302-310
2004
-
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1
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1
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1
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2
1
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5
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1
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650862
Lukacs
Rapid and simple assay for the ...
Homo sapiens
Clin. Chem.
49
509-512
2003
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1
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1
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652459
Calero
The crystal structure of palmi ...
Homo sapiens
J. Biol. Chem.
278
37957-37964
2003
-
-
1
1
1
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1
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1
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2
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1
1
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6
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6
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1
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652624
Ahtiainen
Palmitoyl protein thioesterase ...
Mus musculus
J. Comp. Neurol.
455
368-377
2003
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3
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1
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1
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1
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6
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650368
Lu
The effects of lysosomotropic ...
Homo sapiens
Biochim. Biophys. Acta
1583
35-44
2002
-
-
-
-
-
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2
-
1
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1
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2
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1
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2
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2
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1
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2
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653345
Suopanki
Status epilepticus induces cha ...
Rattus norvegicus
Neurobiol. Dis.
10
247-257
2002
-
-
-
-
-
-
-
-
3
-
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1
-
4
-
1
-
1
-
3
-
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2
1
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3
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1
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1
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3
-
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2
1
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651450
Das
Biochemical analysis of mutati ...
Homo sapiens
Hum. Mol. Genet.
10
1431-1439
2001
-
-
1
-
12
-
-
2
2
-
-
1
-
3
-
1
-
1
-
1
2
-
4
-
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1
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12
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2
2
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1
-
-
1
-
-
1
2
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
651451
Lehtovirta
Palmitoyl protein thioesterase ...
Homo sapiens, Mus musculus
Hum. Mol. Genet.
10
69-75
2001
-
-
2
-
-
-
-
-
4
-
1
2
-
3
-
-
-
2
-
6
-
-
4
1
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
4
-
1
2
-
-
-
-
-
6
-
-
4
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
653226
Salonen
Neuronal trafficking of palmit ...
Homo sapiens
Mol. Cell. Neurosci.
18
131-140
2001
-
-
1
-
3
-
-
-
-
-
-
1
-
3
-
-
-
1
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
3
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
651455
Waliany
Identification of three novel ...
Homo sapiens
Hum. Mutat.
15
206-207
2000
-
-
1
-
7
-
-
-
-
-
-
1
-
2
-
-
-
1
-
2
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
7
-
-
-
-
-
-
-
-
1
-
-
-
-
-
2
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
651456
Salonen
Detection of eight novel palmi ...
Homo sapiens
Hum. Mutat.
15
273-279
2000
-
-
1
-
-
-
-
-
-
-
-
1
-
2
-
-
-
1
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
653651
Bellizzi
The crystal structure of palmi ...
Homo sapiens
Proc. Natl. Acad. Sci. USA
97
4573-4578
2000
-
-
1
1
12
-
-
-
1
-
-
1
-
1
-
1
-
1
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
12
-
-
-
-
-
1
-
-
1
-
-
1
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
653243
Suopanki
The expression of palmitoyl-pr ...
Rattus norvegicus
Mol. Genet. Metab.
66
290-293
1999
-
-
-
-
-
-
-
-
-
-
-
1
-
2
-
-
-
1
-
8
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
8
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
653360
Suopanki
Palmitoyl-protein thioesterase ...
Rattus norvegicus
Neurosci. Lett.
265
53-56
1999
-
-
-
-
-
-
-
-
1
-
-
1
-
2
-
-
-
1
-
10
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
10
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
23910
Cho
Enzymatic and molecular biolog ...
Homo sapiens
J. Neurochem.
71
323-329
1998
-
1
-
-
-
-
-
-
1
-
-
-
-
2
-
-
-
-
-
5
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
5
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
23920
Meng
The antiproliferative agent di ...
Homo sapiens
Biochemistry
37
10488-10492
1998
-
-
1
-
-
-
1
1
-
-
-
-
-
2
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
23919
Michel
The role of palmitoyl-protein ...
Bos taurus
FEBS Lett.
405
356-362
1997
-
-
1
-
-
-
-
-
-
-
-
1
-
1
-
-
1
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
23911
Hellsten
Human palmitoyl protein thioes ...
Homo sapiens
EMBO J.
15
5240-5245
1996
-
-
1
-
-
-
-
-
3
-
-
1
-
2
-
1
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
3
-
-
1
-
-
1
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
23913
Schriner
cDNA and genomic cloning of hu ...
Homo sapiens
Genomics
34
317-4322
1996
-
-
1
-
-
-
-
-
-
-
-
-
-
2
-
1
-
-
-
4
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
4
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
23914
Verkruyse
Lysosomal targeting of palmito ...
Homo sapiens
J. Biol. Chem.
271
15831-15836
1996
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
23917
Slea
Rat brain contains high levels ...
Rattus norvegicus
J. Biol. Chem.
271
19191-19198
1996
-
-
-
-
-
-
-
-
1
-
-
-
-
2
-
1
-
-
-
3
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
3
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
23918
Lu
Lipid thioesters derived from ...
Homo sapiens
Proc. Natl. Acad. Sci. USA
93
10046-10050
1996
-
-
-
-
-
-
-
-
1
-
-
2
-
2
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
23912
Vesa
Mutations in the palmitoyl pro ...
Homo sapiens
Nature
376
584-587
1995
-
-
-
-
-
-
-
-
1
-
-
-
-
2
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
23915
Camp
Assay and isolation of palmito ...
Bos taurus
Methods Enzymol.
250
336-347
1995
-
-
-
-
-
1
1
-
1
-
-
-
-
2
-
-
1
-
-
2
1
1
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
1
-
-
-
-
-
-
1
-
2
1
1
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
23916
Camp
Purification and properties of ...
Bos taurus
J. Biol. Chem.
268
22566-22574
1993
-
-
-
-
-
-
3
2
-
-
1
-
-
2
-
-
1
-
-
1
-
-
4
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
2
-
-
1
-
-
-
-
1
-
1
-
-
4
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-