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Literature summary for 3.1.2.2 extracted from

  • Takagi, M.; Yamakawa, H.; Watanabe, T.; Suga, T.; Yamada, J.
    Inducible expression of long-chain acyl-CoA hydrolase gene in cell cultures (2003), Mol. Cell. Biochem., 252, 379-385.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
BACH, stable expression in C3H 10T1/2 fibroblastic cell line using an mifepristone (RU486)-inducible expression system as C-terminally MYC-tagged enzyme Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
palmitoyl-CoA + H2O Mus musculus the enzyme affects specifically cellular systems and functions, but not all acyl-CoA-utilizing processes, overexpression leads to reduction of growth rate but not to phospholipid synthesis CoA + palmitate
-
?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Mus musculus
-
neuron
-
Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
palmitoyl-CoA + H2O
-
Mus musculus CoA + palmitate
-
?
palmitoyl-CoA + H2O the enzyme affects specifically cellular systems and functions, but not all acyl-CoA-utilizing processes, overexpression leads to reduction of growth rate but not to phospholipid synthesis Mus musculus CoA + palmitate
-
?

Synonyms

Synonyms Comment Organism
BACH
-
Mus musculus
long-chain acyl-CoA hydrolase
-
Mus musculus