Literature summary for 3.1.2.2 extracted from

Kuramochi, Y.; Takagi-Sakuma, M.; Kitahara, M.; Emori, R.; Asaba, Y.; Sakaguchi, R.; Watanabe, T.; Kuroda, J.; Hiratsuka, K.; Nagae, Y.; Suga, T.; Yamada, J.
Characterization of mouse homolog of brain acyl-CoA hydrolase: molecular cloning and neuronal localization (2002), Mol. Brain Res., 98, 81-92.

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Cloned(Commentary)

Cloned (Comment)	Organism
3 isozymes with differences in the 5'-end sequences, DNA and amino acid sequence determination and analysis, gene structure, functional expression in Escherichia coli BL21(DE3), expression in neuroblastoma cell line Neuro-2a	Mus musculus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cytosol	-	Mus musculus	5829	-

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	Q91V12	brain-specific isozyme, 3 isozymes with differences in the 5'-end sequences, overview	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	central and peripheric nervous system, brain-specific isozyme	Mus musculus	-
cerebral cortex	brain-specific isozyme	Mus musculus	-
large intestine	brain-specific isozyme	Mus musculus	-
additional information	palmitoyl-CoA hydrolase activity is widespread in all tissues	Mus musculus	-
neuron	cell body and neurites, brain-specific isozyme	Mus musculus	-
testis	brain-specific isozyme	Mus musculus	-
thymus	brain-specific isozyme	Mus musculus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
palmitoyl-CoA + H2O	broad substrate specificity for long-chain acyl-CoA substrates	Mus musculus	CoA + palmitate	-	?

Subunits

Subunits	Comment	Organism
?	x * 43000-50000, 3 isozymes of BACH, SDS-PAGE	Mus musculus

Synonyms

Synonyms	Comment	Organism
BACH	-	Mus musculus
brain acyl-CoA hydrolase	-	Mus musculus

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Release 2023.1 (January 2023)