Any feedback?
Literature summary for 3.1.2.18 extracted from
- Short- and medium-chain carnitine acyltransferases and acyl-CoA thioesterases in mouse provide complementary systems for transport of beta-oxidation products out of peroxisomes (2008), Cell. Mol. Life Sci., 65, 982-990.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| peroxisome | - |
Mus musculus | 5777 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| an acyl-CoA + H2O | Mus musculus | - |
CoA + a carboxylate | - |
? |  |
| additional information | Mus musculus | acyl-CoA thioesterase produces free fatty acids | ? | - |
? | |
| additional information | Mus musculus | peroxisomal carnitine acyl-CoA thioesterases and acyltransferases are differently expressed to function as complementary enzymes for transport of beta-oxidation metabolites | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
male Sv/129 mice | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | low expression of Acot12 | Mus musculus | - |
| brown adipose tissue | low expression of Acot12 | Mus musculus | - |
| heart | low expression of Acot12 | Mus musculus | - |
| intestine | proximal, high expression of Acot12 | Mus musculus | - |
| kidney | high expression of Acot12 | Mus musculus | - |
| liver | high expression of Acot12 | Mus musculus | - |
| lung | low expression of Acot12 | Mus musculus | - |
| spleen | low expression of Acot12 | Mus musculus | - |
| white adipose tissue | low expression of Acot12 | Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| an acyl-CoA + H2O | - |
Mus musculus | CoA + a carboxylate | - |
? | |
| additional information | acyl-CoA thioesterase produces free fatty acids | Mus musculus | ? | - |
? | |
| additional information | peroxisomal carnitine acyl-CoA thioesterases and acyltransferases are differently expressed to function as complementary enzymes for transport of beta-oxidation metabolites | Mus musculus | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Acot12 | - |
Mus musculus |
| Acot15 | - |
Mus musculus |
| Acot8 | - |
Mus musculus |
| acyl-CoA hydrolase | - |
Mus musculus |
| acyl-CoA thioesterase | - |
Mus musculus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ADP | - |
Mus musculus | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
