Literature summary for 3.1.15.1 extracted from

Huo, C.H.; Shen, L.R.; Zhao, Y.Y.; Liang, H.
Chemical constituents of plants from the genus Symplocos (2007), Chem. Biodivers., 4, 1-11.

Search for more literature for 3.1.15.1

Application

Application	Comment	Organism
medicine	some phenolic glycoside derivatives show inhibitory activity against snake venom phosphodiesterase I. Compounds are potential candidates for the therapy of snake bites	Crotalus adamanteus

Inhibitors

Inhibitors	Comment	Organism	Structure
benzoyl salireposide	shows strong inhibitory activity	Crotalus adamanteus
salireposide	shows moderate inhibitory activity	Crotalus adamanteus
symplomoside	shows weak inhibitory activity	Crotalus adamanteus
symploracemoside	shows moderate inhibitory activity	Crotalus adamanteus

Organism

Organism	UniProt	Comment	Textmining
Crotalus adamanteus	-	-	-

Synonyms

Synonyms	Comment	Organism
snake venom phosphodiesterase I	-	Crotalus adamanteus

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
0.171	-	-	Crotalus adamanteus	benzoyl salireposide
0.544	-	-	Crotalus adamanteus	salireposide
0.59	-	-	Crotalus adamanteus	symploracemoside
0.998	-	-	Crotalus adamanteus	symplomoside

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Release 2023.1 (January 2023)