Any feedback?
Literature summary for 3.1.13.4 extracted from
- Nocturnin at the crossroads of clocks and metabolism (2012), Trends Endocrinol. Metab., 23, 326-333 .
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| mRNA-poly(A) + H2O | Mus musculus | the enzyme is involved in the removal of polyA tails from mRNAs | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | O35710 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| mRNA-poly(A) + H2O | the enzyme is involved in the removal of polyA tails from mRNAs | Mus musculus | ? | - |
? | |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | mice lacking the Noc gene display resistance to diet-induced obesity and hepatic steatosis, due in part to reduced lipid trafficking in the small intestine | Mus musculus |
| physiological function | the enzyme is involved in the removal of polyA tails from mRNAs. Noc is a potential key post-transcriptional mediator in the circadian control of many metabolic processes. It appears to play important roles in other tissues and has been implicated in lipid metabolism, adipogenesis, glucose homeostasis, inflammation and osteogenesis | Mus musculus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
