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Literature summary for 3.1.13.2 extracted from

  • Leo, B.; Schweimer, K.; Roesch, P.; Hartl, M.J.; Woehrl, B.M.
    The solution structure of the prototype foamy virus RNase H domain indicates an important role of the basic loop in substrate binding (2012), Retrovirology, 9, 73.
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
C654S the mutant shows wild type activity Human spumaretrovirus
D599N/H742N the RNase H activity of the mutant is seriously impaired Human spumaretrovirus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
18000
-
x * 18000, estimateted from amino acid sequence Human spumaretrovirus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
DNA-RNA hybrid + H2O Human spumaretrovirus
-
?
-
?

Organism

Organism UniProt Comment Textmining
Human spumaretrovirus P14350 foamy virus
-

Purification (Commentary)

Purification (Comment) Organism
-
Human spumaretrovirus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
DNA-RNA hybrid + H2O
-
Human spumaretrovirus ?
-
?

Subunits

Subunits Comment Organism
? x * 18000, estimateted from amino acid sequence Human spumaretrovirus

Synonyms

Synonyms Comment Organism
ribonuclease H
-
Human spumaretrovirus
RNase H
-
Human spumaretrovirus