Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.1.13.2 extracted from

  • Ehteshami, M.; Goette, M.
    Effects of mutations in the connection and RNase H domains of HIV-1 reverse transcriptase on drug susceptibility (2008), AIDS Rev., 10, 224-235.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
additional information mutations in the C-terminus of HIV-1 reverse transcriptase, C-terminal reverse transcriptase mutations are resistant to both nucleoside analog reverse transcriptase inhibitor and nonnucleoside reverse transcriptase inhibitor. Other mutations are reviewed Human immunodeficiency virus 1

Inhibitors

Inhibitors Comment Organism Structure
nonnucleoside reverse transcriptase inhibitor NNRTI Human immunodeficiency virus 1
nucleoside analog reverse transcriptase inhibitor NRTI Human immunodeficiency virus 1

Organism

Organism UniProt Comment Textmining
Human immunodeficiency virus 1
-
-
-

Synonyms

Synonyms Comment Organism
RNase H domain of HIV-1 reverse transcriptase Human immunodeficiency virus 1