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Literature summary for 3.1.11.6 extracted from

  • Rudolph, C.J.; Mahdi, A.A.; Upton, A.L.; Lloyd, R.G.
    RecG protein and single-strand DNA exonucleases avoid cell lethality associated with PriA helicase activity in Escherichia coli (2010), Genetics, 186, 473-492.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.11.6

Protein Variants

Protein Variants Comment Organism
additional information conbstruction of ExoVII-deficient cells and of cells lacking alll three exonuxleases, exonuclease I, exonuclease VII, or SbcCD, phenotypes, detailed overview Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Escherichia coli exonuclease VII can digest ssDNA from 3' ends ?
-
 ?
additional information Escherichia coli K-12, MG1655 exonuclease VII can digest ssDNA from 3' ends ?
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-
Escherichia coli K-12, MG1655
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information exonuclease VII can digest ssDNA from 3' ends Escherichia coli ?
-
 ?
additional information exonuclease VII can digest ssDNA from 3' ends Escherichia coli K-12, MG1655 ?
-
 ?

Synonyms

Synonyms Comment Organism
exonuclease VII
-
 Escherichia coli
ExoVII
-
 Escherichia coli

General Information

General Information Comment Organism
malfunction ExoI- ExoVII- SbcCD- cells are sensitive to mitomycin C and 2-aminopurine. Cells lacking all three nucleases, exonuclease I, exonuclease VII, or SbcCD, are inviable without RecG. Removing RNase HI mimics the effect of removing RecG in that DrnhA cells are inviable if ExoI, ExoVII, and SbcCD are eliminated Escherichia coli
physiological function to stay alive, cells must have either RecG or a 3'-single-stranded DNA exonuclease, which can be exonuclease I, exonuclease VII, or SbcCD. Cells lacking all three nucleases are inviable without RecG Escherichia coli