Any feedback?
Literature summary for 3.1.11.1 extracted from
- Protection of oligodeoxynucleotides against nuclease degradation through association with self-assembling peptides (2008), Biomaterials, 29, 1099-1108.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | self-assembling peptide EAK-oligodeoxynucleotide aggregates generated with EAK16IV at pH 4 are not degraded by exonuclease I even after 90 min. Fl-dC16-Rh complexed with EAK16IV at pH 4 shows significant nuclease resistance against exonuclease I. Aggregates prepared with EAK16IV and Fl-dC16-Rh at pH 4 protect Fl-dC16-Rh against nuclease degradation even after being incubated at pH 9.5 for 2 h. Centrifuging the EAK16IV-oligodeoxynucleotide solution immediately after sample preparation results in the loss of this nuclease protection. If the solution of EAK-oligodeoxynucleotide aggregates is centrifuged 24 h after sample preparation, the nuclease protection afforded by the EAK16IVoligodeoxynucleotide aggregates to the oligodeoxynucleotide is maintained even after being subject to a 10fold dilution and up to 4 rounds of centrifugation over 4 days | Escherichia coli | ? | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| exonuclease I | - |
Escherichia coli |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
