Protein Variants | Comment | Organism |
---|---|---|
E219T | the mutant is active at wild type levels | Ochrobactrum sp. T63 |
G100V | inactive | Ochrobactrum sp. T63 |
G104V | inactive | Ochrobactrum sp. T63 |
H248S | inactive | Ochrobactrum sp. T63 |
S102V | inactive | Ochrobactrum sp. T63 |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mn2+ | the N-acyl-(S)-homoserine lactone-inactivating activity of the enzyme requires Mn2+ | Ochrobactrum sp. T63 | |
additional information | not affected by Ca2+, Mg2+, Cu2+, Fe2+, Zn2+ | Ochrobactrum sp. T63 |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Ochrobactrum sp. T63 | D2J2T6 | - |
- |
Ochrobactrum sp. T63 ATCC 49188 | D2J2T6 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-acyl-(S)-homoserine lactone + H2O | - |
Ochrobactrum sp. T63 | N-acyl-(S)-homoserine | - |
? | |
N-acyl-(S)-homoserine lactone + H2O | - |
Ochrobactrum sp. T63 ATCC 49188 | N-acyl-(S)-homoserine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
AHL-lactonase | - |
Ochrobactrum sp. T63 |
AidH | - |
Ochrobactrum sp. T63 |
N-acylhomoserine lactonase | - |
Ochrobactrum sp. T63 |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme significantly reduces biofilm formation by Pseudomonas fluorescens strain 2P24 and the pathogenicity of Pectobacterium carotovorum indicating that this enzyme is able to effectively quench quorum-sensing-dependent functions in these bacteria by degrading N-acyl-(S)-homoserine lactones | Ochrobactrum sp. T63 |