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Literature summary for 3.1.1.8 extracted from

  • Elsebai, M.; Ghabbour, H.; Marzouk, A.; Salmas, R.; Orhan, I.; Senol, F.
    Amberboin and lipidiol X-ray crystalographic data, absolute configuration and inhibition of cholinesterase (2018), Phytochem. Lett., 27, 44-48 .
No PubMed abstract available
Search for more literature for 3.1.1.8

Inhibitors

Inhibitors Comment Organism Structure
amberboin a sesquiterpene lactone from extract of Volutaria abyssinica, inhibition mechanism Homo sapiens
additional information enzyme-inhibitor binding structure from the crystal structure analysis, molecular docking and modelling, overview. No inhibition by sesquiterpene lactone lipidiol from extract of Volutaria abyssinica Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
butyrylcholine + H2O Homo sapiens
-
 choline + butyrate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens P06276
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood plasma
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
butyrylcholine + H2O
-
 Homo sapiens choline + butyrate
-
 ?

Synonyms

Synonyms Comment Organism
BChE
-
 Homo sapiens
butyrylcholinesterase
-
 Homo sapiens

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.00058
-
 pH and temperature not specified in the publication Homo sapiens amberboin