Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(dibutyl phosphoric) hypochlorous anhydride | - |
Equus caballus | |
benzyl di-n-butyl phosphate | - |
Equus caballus | |
butyl ethyl phenyl phosphate | - |
Equus caballus | |
di-n-butyl 2-chlorophenyl phosphate | irreversible inhibition | Equus caballus | |
di-n-butyl 2-methylbenzyl phosphate | - |
Equus caballus | |
di-n-butyl 2-methylphenyl phosphate | reversible inhibition | Equus caballus | |
di-n-butyl 2-naphthyl phosphate | - |
Equus caballus | |
di-n-butyl 2-phenylethyl phosphate | - |
Equus caballus | |
di-n-butyl 3,4,5-trimethylphenyl phosphate | - |
Equus caballus | |
di-n-butyl 3,4-dimethylphenyl phosphate | - |
Equus caballus | |
di-n-butyl 3,5-dimethylphenyl phosphate | - |
Equus caballus | |
di-n-butyl 3-methylbenzyl phosphate | - |
Equus caballus | |
di-n-butyl 3-methylphenyl phosphate | reversible inhibition | Equus caballus | |
di-n-butyl 4-methylbenzyl phosphate | - |
Equus caballus | |
di-n-butyl 4-methylphenyl phosphate | reversible inhibition | Equus caballus | |
di-n-butyl naphthalen-1-yl phosphate | - |
Equus caballus | |
di-n-butyl phenyl phosphate | - |
Equus caballus | |
di-n-pentyl phenyl phosphate | - |
Equus caballus | |
dicyclohexyl phenyl phosphate | - |
Equus caballus | |
diethyl 2-naphthyl phosphate | - |
Equus caballus | |
diethyl 3,5-dimethylphenyl phosphate | - |
Equus caballus | |
diethyl phenyl phosphate | - |
Equus caballus | |
dimethyl phenyl phosphate | - |
Equus caballus | |
additional information | synthesis, biochemical evaluation, and molecular modeling studies of aryl and arylalkyl di-n-butyl phosphates, effective butyrylcholinesterase inhibitors, overview. Analysis of enzyme binding structure, structure-function analysis, modeling | Equus caballus | |
phenyl dipropyl phosphate | - |
Equus caballus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Equus caballus | P81908 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
commercial preparation | - |
Equus caballus | - |
serum | - |
Equus caballus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
butyrylthiocholine + H2O | - |
Equus caballus | thiocholine + butyrate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
BChE | - |
Equus caballus |
butyrylcholinesterase | - |
Equus caballus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
25 | - |
assay at | Equus caballus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Equus caballus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.001 | - |
di-n-butyl 3,5-dimethylphenyl phosphate | pH 7.5, 25°C | Equus caballus | |
0.0019 | - |
di-n-butyl 2-naphthyl phosphate | pH 7.5, 25°C | Equus caballus | |
0.002 | - |
benzyl di-n-butyl phosphate | pH 7.5, 25°C | Equus caballus | |
0.008 | - |
di-n-butyl 4-methylphenyl phosphate | pH 7.5, 25°C | Equus caballus | |
0.009 | - |
di-n-butyl 3,4-dimethylphenyl phosphate | pH 7.5, 25°C | Equus caballus | |
0.011 | - |
di-n-butyl 3,4,5-trimethylphenyl phosphate | pH 7.5, 25°C | Equus caballus | |
0.014 | - |
di-n-butyl 4-methylbenzyl phosphate | pH 7.5, 25°C | Equus caballus | |
0.016 | - |
di-n-butyl 3-methylphenyl phosphate | pH 7.5, 25°C | Equus caballus | |
0.022 | - |
di-n-butyl naphthalen-1-yl phosphate | pH 7.5, 25°C | Equus caballus | |
0.024 | - |
di-n-butyl 3-methylbenzyl phosphate | pH 7.5, 25°C | Equus caballus | |
0.05 | - |
di-n-butyl 2-methylphenyl phosphate | pH 7.5, 25°C | Equus caballus | |
0.053 | - |
di-n-butyl 2-phenylethyl phosphate | pH 7.5, 25°C | Equus caballus | |
0.072 | - |
di-n-butyl 2-methylbenzyl phosphate | pH 7.5, 25°C | Equus caballus |