Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(+)-debromoflustramine B | - |
Homo sapiens | |
(-)-debromoflustramine B | - |
Homo sapiens | |
1,3a,8-tris(3-methylbut-2-enyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indole | - |
Homo sapiens | |
1-benzyl-5-methoxy-3a,8-bis(3-methylbut-2-enyl)-1,2,3,3a,8,8ahexahydropyrrolo[2,3-b]indole | - |
Homo sapiens | |
3a,8-dibenzyl-1-methyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indole | - |
Homo sapiens | |
3a,8-dibenzyl-5-methoxy-1-methyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indole | - |
Homo sapiens | |
5-methoxy-1-methyl-3a,8-bis(3-methylbut-2-en-1-yl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indole | - |
Homo sapiens | |
8-benzyl-1-methyl-3a-(3-methylbut-2-enyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indole | - |
Homo sapiens | |
8-benzyl-5-methoxy-1-methyl-3a-(3-methylbut-2-enyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indole | - |
Homo sapiens | |
demethyldebromoflustramine B | - |
Homo sapiens | |
galanthamine | - |
Homo sapiens | |
huperzine A | - |
Homo sapiens | |
additional information | structure-activity studies of debromoflustramine B analogues as selective BChE inhibitors, molecular modeling, overview | Homo sapiens | |
physostigmine | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
butyrylcholinesterase | - |
Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00026 | - |
- |
Homo sapiens | demethyldebromoflustramine B | |
0.00137 | - |
- |
Homo sapiens | (-)-debromoflustramine B | |
0.00172 | - |
- |
Homo sapiens | 1,3a,8-tris(3-methylbut-2-enyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indole | |
0.00259 | - |
- |
Homo sapiens | rac debromoflustramine B | |
0.00459 | - |
- |
Homo sapiens | 5-methoxy-1-methyl-3a,8-bis(3-methylbut-2-en-1-yl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indole | |
0.00589 | - |
- |
Homo sapiens | 3a,8-dibenzyl-5-methoxy-1-methyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indole | |
0.00754 | - |
- |
Homo sapiens | 8-benzyl-5-methoxy-1-methyl-3a-(3-methylbut-2-enyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indole | |
0.01 | - |
- |
Homo sapiens | 8-benzyl-1-methyl-3a-(3-methylbut-2-enyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indole | |
0.0221 | - |
- |
Homo sapiens | 3a,8-dibenzyl-1-methyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indole | |
0.04998 | - |
- |
Homo sapiens | 1-benzyl-5-methoxy-3a,8-bis(3-methylbut-2-enyl)-1,2,3,3a,8,8ahexahydropyrrolo[2,3-b]indole | |
10 | - |
- |
Homo sapiens | (+)-debromoflustramine B |