Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.1.1.8 extracted from

  • Calic, M.; Bosak, A.; Kuca, K.; Kovarik, Z.
    Interactions of butane, but-2-ene or xylene-like linked bispyridinium para-aldoximes with native and tabun-inhibited human cholinesterases (2008), Chem. Biol. Interact., 175, 305-308.
    View publication on PubMed
Search for more literature for 3.1.1.8

Inhibitors

Inhibitors Comment Organism Structure
K074 a bispyridinium para-aldoxime with butane linker, reversible inhibition Homo sapiens
K075 a bispyridinium para-aldoxime with but-2-ene linker, reversible inhibition Homo sapiens
K114 a bispyridinium para-aldoxime with xylene-like linker, reversible, noncompetitive inhibition Homo sapiens
Tabun tabun-inhibited enzymes are reactivated by K074, K075, and K114, kinetics, overview Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
 Homo sapiens
-
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood plasma
-
 Homo sapiens
-

Synonyms

Synonyms Comment Organism
BChE
-
 Homo sapiens
butyrylcholinesterase
-
 Homo sapiens

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.059
-
 K114
-
 Homo sapiens
0.127
-
 K074
-
 Homo sapiens
0.338
-
 K075
-
 Homo sapiens