Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Butyrylcholine | competitive to butyrylthiocholine | Homo sapiens | |
butyrylthiocholine | competitive to butyrylcholine | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | structure-activity relationships and kinetic studies, overview | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
butyrylcholine + H2O | - |
Homo sapiens | choline + butyrate | - |
? | |
butyrylthiocholine + H2O | - |
Homo sapiens | thiocholine + butyrate | - |
? | |
additional information | structure-activity relationships and kinetic studies, overview, the enzyme also shows an aryl acylamidase activity, EC 3.5.1.13, whereby it catalyzes the hydrolysis of amides of certain aromatic amines, BuChE shows high activity with larger N-(2-nitrophenyl)alkylamides, the ester and anilide substrates compete for the some catalytic site, no significant hydrolysis of the anilide takes place until the preferred choline ester hydrolysis is completed, overview | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
BuChE | - |
Homo sapiens |
butyrylcholinesterase | - |
Homo sapiens |
ChE | - |
Homo sapiens |
cholinesterase | - |
Homo sapiens |
More | cf. EC 3.5.1.13 | Homo sapiens |