Inhibitors | Comment | Organism | Structure |
---|---|---|---|
10-(2,2-dimethylpropanoyl)-10H-phenothiazine | relative potency EC 3.1.1.8 to EC 3.1.1.7 is 4.7 | Homo sapiens | |
10-(2-ethylbutanoyl)-10H-phenothiazine | not inhibitory to EC 3.1.1.7 | Homo sapiens | |
10-(3,3-dimethylbutanoyl)-10H-phenothiazine | not inhibitory to EC 3.1.1.7 | Homo sapiens | |
10-(3-methylbutanoyl)-10H-phenothiazine | not inhibitory to EC 3.1.1.7 | Homo sapiens | |
10-(chloroacetyl)-10H-phenothiazine | relative potency EC 3.1.1.8 to EC 3.1.1.7 is 7.3 | Homo sapiens | |
10-(cyclobutylcarbonyl)-10H-phenothiazine | relative potency EC 3.1.1.8 to EC 3.1.1.7 is 11.6 | Homo sapiens | |
10-(cycloheptylcarbonyl)-10H-phenothiazine | not inhibitory to EC 3.1.1.7 | Homo sapiens | |
10-(cyclohexylacetyl)-10H-phenothiazine | not inhibitory to EC 3.1.1.7 | Homo sapiens | |
10-(cyclohexylcarbonyl)-10H-phenothiazine | not inhibitory to EC 3.1.1.7 | Homo sapiens | |
10-(cyclopentylacetyl)-10H-phenothiazine | not inhibitory to EC 3.1.1.7 | Homo sapiens | |
10-(cyclopentylcarbonyl)-10H-phenothiazine | not inhibitory to EC 3.1.1.7 | Homo sapiens | |
10-(cyclopropylcarbonyl)-10H-phenothiazine | relative potency EC 3.1.1.8 to EC 3.1.1.7 is 1.9 | Homo sapiens | |
10-(methoxyacetyl)-10H-phenothiazine | relative potency EC 3.1.1.8 to EC 3.1.1.7 is 0.8 | Homo sapiens | |
10-acetyl-10H-phenothiazine | relative potency EC 3.1.1.8 to EC 3.1.1.7 is 1.1 | Homo sapiens | |
10-butyryl-10H-phenothiazine | relative potency EC 3.1.1.8 to EC 3.1.1.7 is 1.9 | Homo sapiens | |
10-heptanoyl-10H-phenothiazine | not inhibitory to EC 3.1.1.7 | Homo sapiens | |
10-hexanoyl-10H-phenothiazine | not inhibitory to EC 3.1.1.7 | Homo sapiens | |
10-isobutyryl-10H-phenothiazine | relative potency EC 3.1.1.8 to EC 3.1.1.7 is 2.7 | Homo sapiens | |
10-pentanoyl-10H-phenothiazine | not inhibitory to EC 3.1.1.7 | Homo sapiens | |
10-propionyl-10H-phenothiazine | relative potency EC 3.1.1.8 to EC 3.1.1.7 is 1.8 | Homo sapiens | |
chlorpromazine | not inhibitory to EC 3.1.1.7 | Homo sapiens | |
ethopropazine | not inhibitory to EC 3.1.1.7 | Homo sapiens | |
N-methylphenothiazine | not inhibitory to EC 3.1.1.7 | Homo sapiens | |
phenothiazine | not inhibitory to EC 3.1.1.7 | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.000166 | - |
ethopropazine | pH 8.0, 23°C | Homo sapiens | |
0.00086 | - |
10-(cycloheptylcarbonyl)-10H-phenothiazine | pH 8.0, 23°C | Homo sapiens | |
0.00126 | - |
10-(cyclohexylcarbonyl)-10H-phenothiazine | pH 8.0, 23°C | Homo sapiens | |
0.00168 | - |
10-(cyclohexylacetyl)-10H-phenothiazine | pH 8.0, 23°C | Homo sapiens | |
0.00222 | - |
10-(cyclopentylacetyl)-10H-phenothiazine | pH 8.0, 23°C | Homo sapiens | |
0.00359 | - |
10-(3,3-dimethylbutanoyl)-10H-phenothiazine | pH 8.0, 23°C | Homo sapiens | |
0.00421 | - |
10-(cyclopentylcarbonyl)-10H-phenothiazine | pH 8.0, 23°C | Homo sapiens | |
0.0048 | - |
10-(cyclobutylcarbonyl)-10H-phenothiazine | pH 8.0, 23°C | Homo sapiens | |
0.00633 | - |
10-(2,2-dimethylpropanoyl)-10H-phenothiazine | pH 8.0, 23°C | Homo sapiens | |
0.00637 | - |
10-hexanoyl-10H-phenothiazine | pH 8.0, 23°C | Homo sapiens | |
0.00643 | - |
10-(2-ethylbutanoyl)-10H-phenothiazine | pH 8.0, 23°C | Homo sapiens | |
0.00646 | - |
10-(3-methylbutanoyl)-10H-phenothiazine | pH 8.0, 23°C | Homo sapiens | |
0.00831 | - |
10-heptanoyl-10H-phenothiazine | pH 8.0, 23°C | Homo sapiens | |
0.0102 | - |
10-pentanoyl-10H-phenothiazine | pH 8.0, 23°C | Homo sapiens | |
0.0109 | - |
10-(chloroacetyl)-10H-phenothiazine | pH 8.0, 23°C | Homo sapiens | |
0.0132 | - |
10-isobutyryl-10H-phenothiazine | pH 8.0, 23°C | Homo sapiens | |
0.0162 | - |
10-butyryl-10H-phenothiazine | pH 8.0, 23°C | Homo sapiens | |
0.0231 | - |
10-(cyclopropylcarbonyl)-10H-phenothiazine | pH 8.0, 23°C | Homo sapiens | |
0.0256 | - |
10-propionyl-10H-phenothiazine | pH 8.0, 23°C | Homo sapiens | |
0.0296 | - |
10-(methoxyacetyl)-10H-phenothiazine | pH 8.0, 23°C | Homo sapiens | |
0.0318 | - |
phenothiazine | pH 8.0, 23°C | Homo sapiens | |
0.0322 | - |
chlorpromazine | pH 8.0, 23°C | Homo sapiens | |
0.0358 | - |
10-acetyl-10H-phenothiazine | pH 8.0, 23°C | Homo sapiens | |
0.0369 | - |
N-methylphenothiazine | pH 8.0, 23°C | Homo sapiens |