Literature summary for 3.1.1.79 extracted from

De Koster, J.; Nelli, R.; Strieder-Barboza, C.; de Souza, J.; Lock, A.; Contreras, G.
The contribution of hormone sensitive lipase to adipose tissue lipolysis and its regulation by insulin in periparturient dairy cows (2018), Sci. Rep., 8, 13378 .

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Inhibitors

Inhibitors	Comment	Organism	Structure
CAY10499	in periparturient dairy cows, the compound inhibits basal lipolysis negligibly at 11 d prepartum, but at 11 and 24 d postpartum it reduces basal lipolysis by 36.1% and 43.1%, respectively	Bos taurus

Organism

Organism	UniProt	Comment	Textmining
Bos taurus	P16386	-	-

General Information

General Information	Comment	Organism
physiological function	HSL contribution to basal lipolysis is negligible prepartum in periparturient dairy cows. HSL is a major driver of subcutaneous adipose tissue lipolytic responses postpartum. Reduced lipogenesis is an important contributor to fatty acid release from subcutaneous adipose tissue	Bos taurus

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Release 2023.1 (January 2023)