Literature summary for 3.1.1.79 extracted from

Ben Ali, Y.; Carriere, F.; Verger, R.; Petry, S.; Muller, G.; Abousalham, A.
Continuous monitoring of cholesterol oleate hydrolysis by hormone-sensitive lipase and other cholesterol esterases (2005), J. Lipid Res., 46, 994-1000.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Homo sapiens	hormone-sensitive lipase may be the rate-limiting enzyme controlling the cellular catabolism of diacylglycerol in adipose tissue and that of cholesteryl esters in macrophage foam cells and steroidogenic tissues releasing the cholesterol required for adrenal steroidogenesis	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	recombinant	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
18	-	-	Homo sapiens

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
cholesteryl oleate + H2O	-	Homo sapiens	cholesterol + oleate	-	?
additional information	hormone-sensitive lipase may be the rate-limiting enzyme controlling the cellular catabolism of diacylglycerol in adipose tissue and that of cholesteryl esters in macrophage foam cells and steroidogenic tissues releasing the cholesterol required for adrenal steroidogenesis	Homo sapiens	?	-	?

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Release 2023.1 (January 2023)