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Literature summary for 3.1.1.79 extracted from
- Expression, activity, and localization of hormone-sensitive lipase in rat mammary gland during pregnancy and lactation (2005), J. Lipid Res., 46, 658-668.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| adipocyte | - |
Rattus norvegicus | - |
| mammary gland | in virgin rats, immunoreactive hormone-sensitive lipase is observed in mammary adipocytes, diffuse staining is detected in epithelial cells. Positive staining for hormone-sensitive lipase is detected in the two types of cells in pregnant and lactating animals. As pregnancy advances, the staining intensity of immunoreactive hormone-sensitive lipase increases in the epithelial cells parallel to their proliferation, attaining the maximum during lactation. Both hormone-sensitive lipase protein and activity are lower in mammary glands from 20 and 21 day pregnant rats than from those of virgin rats. They return to virgin values on days 1 and 4 of lactation | Rattus norvegicus | - |
| milk | - |
Rattus norvegicus | - |
| white adipose tissue | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 1,2-dioleoyl-sn-glycerol + H2O | - |
Rattus norvegicus | ? | - |
? |  |
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