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Literature summary for extracted from

  • Lu, M.; Varley, A.W.; Ohta, S.; Hardwick, J.; Munford, R.S.
    Host inactivation of bacterial lipopolysaccharide prevents prolonged tolerance following gram-negative bacterial infection (2008), Cell host microbe, 4, 293-302.
    View publication on PubMedView publication on EuropePMC


Protein Variants Comment Organism
additional information AOAH-deficient (Aoah-/-) mice, recovery from the tolerant state induced by Gram-negative bacteria is greatly delayed in mice that lack acyloxyacyl hydrolase (AOAH). Wild-type mice regain normal responsiveness within 14 days after they receive an intraperitoneal injection of LPS or Gram-negative bacteria, AOAH-deficient mice have greatly reduced proinflammatory responses to a second LPS injection for at least 3 weeks Mus musculus


Organism UniProt Comment Textmining
Mus musculus O35298


Synonyms Comment Organism
acyloxyacyl hydrolase
Mus musculus
Mus musculus