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Literature summary for 3.1.1.77 extracted from

  • Mc Dermott, C.M.; Cullor, J.S.; Fenwick, B.W.
    Intracellular and extracellular enzymatic deacylation of bacterial endotoxin during localized inflammation induced by Escherichia coli (1991), Infect. Immun., 59, 487-485.
No PubMed abstract available
Search for more literature for 3.1.1.77

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3-(acyloxy)acyl group of bacterial toxin Homo sapiens detoxification of LPS 3-hydroxyacyl group of bacterial toxin + a fatty acid
-
 ?
3-(acyloxy)acyl group of bacterial toxin Bos taurus detoxification of LPS 3-hydroxyacyl group of bacterial toxin + a fatty acid
-
 ?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HL-60 cell
-
 Homo sapiens
-
milk cell free Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-(acyloxy)acyl group of bacterial toxin detoxification of LPS Homo sapiens 3-hydroxyacyl group of bacterial toxin + a fatty acid
-
 ?
3-(acyloxy)acyl group of bacterial toxin detoxification of LPS Bos taurus 3-hydroxyacyl group of bacterial toxin + a fatty acid
-
 ?
3-(acyloxy)acyl group of bacterial toxin + H2O
-
 Homo sapiens 3-hydroxyacyl group of bacterial toxin + a fatty acid
-
 ?
3-(acyloxy)acyl group of bacterial toxin + H2O
-
 Bos taurus 3-hydroxyacyl group of bacterial toxin + a fatty acid
-
 ?

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
80
-
 10 min causes complete inactivation Bos taurus

pH Range

pH Minimum pH Maximum Comment Organism
4 7
-
 Bos taurus
4.5 5.5
-
 Homo sapiens