Activating Compound | Comment | Organism | Structure |
---|---|---|---|
dimethylsulfate | induces enzyme activity when added to the medium | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-mercaptoethanol | complete inhibition at 0.1 M | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00055 | - |
lipopolysaccharide | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Homo sapiens | 16020 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
14000 | 20000 | small subunit, SDS-PAGE in presence of 2-mercaptoethanol | Homo sapiens |
48000 | - |
SDS-PAGE of large subunit after N-glycanase treatment | Homo sapiens |
50000 | - |
large subunit, SDS-PAGE in presence of 2-mercaptoethanol | Homo sapiens |
52000 | 60000 | native PAGE | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
3-(acyloxy)acyl group of bacterial toxin | Homo sapiens | detoxification of LPS | 3-hydroxyacyl group of bacterial toxin + a fatty acid | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | both subunits glycosylated | Homo sapiens |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HL-60 cell | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.000005 | - |
cell lysate | Homo sapiens |
1.555 | - |
purified enzyme | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3-(acyloxy)acyl group of bacterial toxin | detoxification of LPS | Homo sapiens | 3-hydroxyacyl group of bacterial toxin + a fatty acid | - |
? | |
3-(acyloxy)acyl group of bacterial toxin + H2O | - |
Homo sapiens | 3-hydroxyacyl group of bacterial toxin + a fatty acid | - |
? | |
lipopolysaccharide + H2O | - |
Homo sapiens | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | alpha, beta, 1 * 50000 + 1 * 14000-20000, disulfide linked | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
4.8 | 5 | - |
Homo sapiens |