Any feedback?
Literature summary for 3.1.1.7 extracted from
- Kinetic analysis of interactions of paraoxon and oximes with human, Rhesus monkey, swine, rabbit, rat and guinea pig acetylcholinesterase (2011), Toxicol. Lett., 200, 19-23.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| HI-6 | - |
Cavia porcellus |  |
| HI-6 | - |
Homo sapiens | |
| HI-6 | - |
Oryctolagus cuniculus | |
| HI-6 | - |
Rattus norvegicus | |
| HI-6 | - |
Sus scrofa | |
| MMB-4 | - |
Cavia porcellus | |
| MMB-4 | - |
Homo sapiens | |
| MMB-4 | - |
Oryctolagus cuniculus | |
| MMB-4 | - |
Rattus norvegicus | |
| MMB-4 | - |
Sus scrofa | |
| obidoxime | - |
Cavia porcellus | |
| obidoxime | - |
Homo sapiens | |
| obidoxime | - |
Oryctolagus cuniculus | |
| obidoxime | - |
Rattus norvegicus | |
| obidoxime | - |
Sus scrofa | |
| paraoxon | - |
Cavia porcellus | |
| paraoxon | - |
Homo sapiens | |
| paraoxon | - |
Oryctolagus cuniculus | |
| paraoxon | - |
Rattus norvegicus | |
| paraoxon | - |
Sus scrofa | |
| pralidoxime | - |
Cavia porcellus | |
| pralidoxime | - |
Homo sapiens | |
| pralidoxime | - |
Oryctolagus cuniculus | |
| pralidoxime | - |
Rattus norvegicus | |
| pralidoxime | - |
Sus scrofa | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acetylcholine + H2O | Cavia porcellus | - |
choline + acetate | - |
? | |
| acetylcholine + H2O | Homo sapiens | - |
choline + acetate | - |
? | |
| acetylcholine + H2O | Rattus norvegicus | - |
choline + acetate | - |
? | |
| acetylcholine + H2O | Sus scrofa | - |
choline + acetate | - |
? | |
| acetylcholine + H2O | Oryctolagus cuniculus | - |
choline + acetate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Cavia porcellus | - |
- |
- |
| Homo sapiens | - |
- |
- |
| Oryctolagus cuniculus | - |
- |
- |
| Rattus norvegicus | - |
- |
- |
| Sus scrofa | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| erythrocyte | - |
Cavia porcellus | - |
| erythrocyte | - |
Homo sapiens | - |
| erythrocyte | - |
Rattus norvegicus | - |
| erythrocyte | - |
Sus scrofa | - |
| erythrocyte | - |
Oryctolagus cuniculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acetylcholine + H2O | - |
Cavia porcellus | choline + acetate | - |
? | |
| acetylcholine + H2O | - |
Homo sapiens | choline + acetate | - |
? | |
| acetylcholine + H2O | - |
Rattus norvegicus | choline + acetate | - |
? | |
| acetylcholine + H2O | - |
Sus scrofa | choline + acetate | - |
? | |
| acetylcholine + H2O | - |
Oryctolagus cuniculus | choline + acetate | - |
? | |
| acetylthiocholine + H2O | - |
Cavia porcellus | thiocholine + acetate | - |
? | |
| acetylthiocholine + H2O | - |
Homo sapiens | thiocholine + acetate | - |
? | |
| acetylthiocholine + H2O | - |
Rattus norvegicus | thiocholine + acetate | - |
? | |
| acetylthiocholine + H2O | - |
Sus scrofa | thiocholine + acetate | - |
? | |
| acetylthiocholine + H2O | - |
Oryctolagus cuniculus | thiocholine + acetate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| AChE | - |
Cavia porcellus |
| AChE | - |
Homo sapiens |
| AChE | - |
Rattus norvegicus |
| AChE | - |
Sus scrofa |
| AChE | - |
Oryctolagus cuniculus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
