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Literature summary for 3.1.1.7 extracted from
- Acetylcholinesterase of Stomoxys calcitrans (L.) (Diptera: Muscidae): cDNA sequence, baculovirus expression, and biochemical properties (2012), Vet. Parasitol., 184, 92-95.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in baculovirus-infected Sf21 insect cells | Stomoxys calcitrans |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| coroxon | - |
Stomoxys calcitrans |  |
| eserine | i.e. physostigamine | Stomoxys calcitrans | |
| paraoxon | - |
Stomoxys calcitrans | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0639 | - |
acetylthiocholine | in potassium phosphate buffer (100 mM, pH 7.5), at 25°C | Stomoxys calcitrans | |
| 0.0967 | - |
butyrylthiocholine | in potassium phosphate buffer (100 mM, pH 7.5), at 25°C | Stomoxys calcitrans | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 77573 | - |
x * 77573, calculated from amino acid sequence | Stomoxys calcitrans |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Stomoxys calcitrans | F8QV18 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| head | - |
Stomoxys calcitrans | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acetylthiocholine + H2O | - |
Stomoxys calcitrans | thiocholine + acetate | - |
? | |
| butyrylthiocholine + H2O | - |
Stomoxys calcitrans | thiocholine + butyrate | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 77573, calculated from amino acid sequence | Stomoxys calcitrans |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| AChE | - |
Stomoxys calcitrans |
pI Value
| Organism | Comment | pI Value Maximum | pI Value |
|---|---|---|---|
| Stomoxys calcitrans | calculated from amino acid sequence | - |
5.8 |
IC50 Value
| IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|
| 0.000005 | - |
in potassium phosphate buffer (100 mM, pH 7.5), at 25°C | Stomoxys calcitrans | eserine | |
| 0.0000064 | - |
in potassium phosphate buffer (100 mM, pH 7.5), at 25°C | Stomoxys calcitrans | coroxon | |
| 0.000195 | - |
in potassium phosphate buffer (100 mM, pH 7.5), at 25°C | Stomoxys calcitrans | paraoxon | |
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