Cloned (Comment) | Organism |
---|---|
expressed in Drosophila S2 cells | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
edrophonium | the inhibitor binds specifically to the A-site of the enzyme | Homo sapiens | |
propidium | the inhibitor binds specifically to the P-site of the enzyme | Homo sapiens | |
thioflavin T | the P-site-specific ligand inhibits the hydrolysis of the rapidly hydrolyzed substrate acetylthiocholine but fails to show any inhibition of the slowly hydrolyzed substrates 3-(acetamido)-N,N,N-trimethylanilinium and carbachol | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3-(acetamido)-N,N,N-trimethylanilinium + H2O | slow hydrolysis | Homo sapiens | ? | - |
? | |
acetylcholine + H2O | fast hydrolysis | Homo sapiens | choline + acetate | - |
? | |
acetylthiocholine + H2O | fast hydrolysis | Homo sapiens | thiocholine + acetate | - |
? | |
carbachol + H2O | slow hydrolysis | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
AChE | - |
Homo sapiens |