Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(7S,9R)-ar-turmerol | a synthetic bisabolane-type sesquiterpenoid derivative | Homo sapiens | |
(7S,9R)-dihydro-arturmerol | a synthetic bisabolane-type sesquiterpenoid derivative | Homo sapiens | |
(7S,9S)-arturmerol | a synthetic bisabolane-type sesquiterpenoid derivative | Homo sapiens | |
(7S,9S)-dihydro-ar-turmerol | a synthetic bisabolane-type sesquiterpenoid derivative | Homo sapiens | |
(S)-ar-curcumene | a synthetic bisabolane-type sesquiterpenoid derivative | Homo sapiens | |
(S)-ar-turmerone | sesquiterpenoid, a competitive inhibitor | Homo sapiens | |
(S)-dihydro-ar-curcumene | a synthetic bisabolane-type sesquiterpenoid derivative | Homo sapiens | |
(S)-dihydro-ar-turmerone | a sesquiterpenoid, a noncompetitive inhibitor | Homo sapiens | |
additional information | chemical compositions and acetylcholinesterase inhibitory activitiy of the volatile oil from the bark of Peltophorum dasyrachis, yellow batai, IC50 value is 0.083 mg/ml, overview. The order of AChE inhibitory potency by bisabolane-type sesquiterpenoids is: ketones > alcohols > hydrocarbons, Structure-activity relationships of inhibitors, overview | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetylcholine + H2O | Homo sapiens | - |
acetate + choline | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetylcholine + H2O | - |
Homo sapiens | acetate + choline | - |
? |
Synonyms | Comment | Organism |
---|---|---|
AChE | - |
Homo sapiens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | inhibition kinetics, overview | Homo sapiens | |
0.882 | - |
(S)-ar-turmerone | - |
Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0815 | - |
- |
Homo sapiens | (S)-dihydro-ar-turmerone | |
0.1911 | - |
- |
Homo sapiens | (S)-ar-turmerone |