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Literature summary for 3.1.1.7 extracted from

  • Ghadimi, S.; Mousavi, S.L.; Javani, Z.
    Synthesis, lipophilicity study and in vitro evaluation of some rodenticides as acetylcholinesterase reversible inhibitors (2008), J. Enzyme Inhib. Med. Chem., 23, 213-217.
    View publication on PubMed
Search for more literature for 3.1.1.7

Inhibitors

Inhibitors Comment Organism Structure
additional information quantitative structure-activity relationships, overview Homo sapiens
N,N-dimethyl phosphoramidic acid bis-(4-chlorophenyl) ester binding activity and lipophilicity, overview Homo sapiens
N,N-dimethyl phosphoramidic acid bis-(4-methylphenyl) ester binding activity and lipophilicity, overview Homo sapiens
N,N-dimethyl phosphoramidic acid bis-phenyl ester binding activity and lipophilicity, overview Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
commercial preparation
-
 Homo sapiens
-
erythrocyte
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetylthiocholine + H2O
-
 Homo sapiens acetate + thiocholine
-
 ?

Synonyms

Synonyms Comment Organism
AChE
-
 Homo sapiens

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
31.3
-
-
 Homo sapiens N,N-dimethyl phosphoramidic acid bis-phenyl ester
35.4
-
-
 Homo sapiens N,N-dimethyl phosphoramidic acid bis-(4-methylphenyl) ester
40.9
-
-
 Homo sapiens N,N-dimethyl phosphoramidic acid bis-(4-chlorophenyl) ester