Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-chlorophenyl 1,2-dimethylhydrazinecarboxylate | - |
Bos taurus | |
2-chlorophenyl 1,2-dimethylhydrazinecarboxylate | - |
Electrophorus electricus | |
2-chlorophenyl 1-methylhydrazinecarboxylate | - |
Bos taurus | |
2-chlorophenyl 1-methylhydrazinecarboxylate | - |
Electrophorus electricus | |
3-chlorophenyl 1,2-dimethylhydrazinecarboxylate | - |
Bos taurus | |
3-chlorophenyl 1,2-dimethylhydrazinecarboxylate | - |
Electrophorus electricus | |
3-chlorophenyl 1-methylhydrazinecarboxylate | - |
Bos taurus | |
3-chlorophenyl 1-methylhydrazinecarboxylate | - |
Electrophorus electricus | |
3-N,N-diethylaminophenyl-N'-(1-alkyl) carbamates | inhibit quickly by carbamoylation | Bos taurus | |
3-N,N-diethylaminophenyl-N'-(1-alkyl) carbamates | inhibit quickly by carbamoylation | Electrophorus electricus | |
3-N,N-diethylaminophenyl-N'-(1-butyl) carbamate | - |
Bos taurus | |
3-N,N-diethylaminophenyl-N'-(1-butyl) carbamate | - |
Electrophorus electricus | |
3-N,N-diethylaminophenyl-N'-(1-ethyl) carbamate | - |
Bos taurus | |
3-N,N-diethylaminophenyl-N'-(1-ethyl) carbamate | - |
Electrophorus electricus | |
3-N,N-diethylaminophenyl-N'-(1-hexyl) carbamate | - |
Bos taurus | |
3-N,N-diethylaminophenyl-N'-(1-hexyl) carbamate | - |
Electrophorus electricus | |
3-N,N-diethylaminophenyl-N'-(1-octyl) carbamate | - |
Bos taurus | |
3-N,N-diethylaminophenyl-N'-(1-octyl) carbamate | - |
Electrophorus electricus | |
3-N,N-diethylaminophenyl-N'-(1-propyl) carbamate | - |
Bos taurus | |
3-N,N-diethylaminophenyl-N'-(1-propyl) carbamate | - |
Electrophorus electricus | |
4-chlorophenyl 1,2-dimethylhydrazinecarboxylate | - |
Bos taurus | |
4-chlorophenyl 1,2-dimethylhydrazinecarboxylate | - |
Electrophorus electricus | |
4-chlorophenyl 1-methylhydrazinecarboxylate | - |
Bos taurus | |
4-chlorophenyl 1-methylhydrazinecarboxylate | - |
Electrophorus electricus | |
additional information | some inhibitors fullfill the competitive inhibition model with irreversible reaction between enzyme and inhibitor, but e.g. not galantamin | Bos taurus | |
additional information | some inhibitors fullfill the competitive inhibition model with irreversible reaction between enzyme and inhibitor, but e.g. not galantamin | Electrophorus electricus | |
phenyl 1,2-dimethylhydrazinecarboxylate | - |
Bos taurus | |
phenyl 1,2-dimethylhydrazinecarboxylate | - |
Electrophorus electricus | |
phenyl 1-methylhydrazinecarboxylate | - |
Bos taurus | |
phenyl 1-methylhydrazinecarboxylate | - |
Electrophorus electricus | |
rivastigmin | - |
Bos taurus | |
rivastigmin | - |
Electrophorus electricus | |
sevin | - |
Bos taurus | |
sevin | - |
Electrophorus electricus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetylcholine + H2O | Bos taurus | - |
choline + acetate | - |
? | |
acetylcholine + H2O | Electrophorus electricus | - |
choline + acetate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Electrophorus electricus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
erythrocyte | - |
Bos taurus | - |
erythrocyte | - |
Electrophorus electricus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
3.5 | - |
- |
Bos taurus |
3.5 | - |
- |
Electrophorus electricus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetylcholine + H2O | - |
Bos taurus | choline + acetate | - |
? | |
acetylcholine + H2O | - |
Electrophorus electricus | choline + acetate | - |
? | |
acetylthiocholine + H2O | - |
Bos taurus | thiocholine + acetate | - |
? | |
acetylthiocholine + H2O | - |
Electrophorus electricus | thiocholine + acetate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
AChE | - |
Bos taurus |
AChE | - |
Electrophorus electricus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
25 | - |
assay at | Bos taurus |
25 | - |
assay at | Electrophorus electricus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8 | - |
assay at | Bos taurus |
8 | - |
assay at | Electrophorus electricus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | inhibition kinetics, value of carbamoylation inhibition | Bos taurus | |
additional information | - |
additional information | inhibition kinetics, value of carbamoylation inhibition | Electrophorus electricus |