Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3-[10-(benzylmethylamino)decyloxy]xanthen-9-one | - |
Homo sapiens | |
3-[11-(benzylmethylamino)undecyloxy]xanthen-9-one | - |
Homo sapiens | |
3-[12-(benzylmethylamino)dodecyloxy]xanthen-9-one | - |
Homo sapiens | |
3-[3-(benzylmethylamino)propoxy]xanthen-9-one | - |
Homo sapiens | |
3-[3-[(2-methoxybenzyl)methylamino]propoxy]-xanthen-9-one | - |
Homo sapiens | |
3-[4-(benzylmethylamino)butoxy]xanthen-9-one | - |
Homo sapiens | |
3-[5-(benzylmethylamino)pentyloxy]xanthen-9-one | - |
Homo sapiens | |
3-[6-(benzylmethylamino)hexyloxy]xanthen-9-one | - |
Homo sapiens | |
3-[7-(benzylmethylamino)-heptyloxy]xanthen-9-one | - |
Homo sapiens | |
3-[7-(benzylmethylamino)heptyloxy]-6-methoxyxanthen-9-one | - |
Homo sapiens | |
3-[7-[(2,3-dimethoxybenzyl)methylamino]heptyloxy]xanthen-9-one | - |
Homo sapiens | |
3-[7-[(2,5-dimethoxybenzyl)methylamino]heptyloxy]xanthen-9-one | - |
Homo sapiens | |
3-[7-[(2-chlorobenzyl)methylamino]-heptyloxy]-xanthen-9-one | - |
Homo sapiens | |
3-[7-[(2-methoxybenzyl)methylamino]heptyloxy]-xanthen-9-one | - |
Homo sapiens | |
3-[7-[(3-chlorobenzyl)methylamino]-heptyloxy]-xanthen-9-one | - |
Homo sapiens | |
3-[7-[(3-methoxybenzyl)methylamino]heptyloxy]-xanthen-9-one | - |
Homo sapiens | |
3-[7-[(4-chlorobenzyl)methylamino]-heptyloxy]-xanthen-9-one | - |
Homo sapiens | |
3-[7-[(4-methoxybenzyl)methylamino]heptyloxy]-xanthen-9-one | - |
Homo sapiens | |
3-[7-[ethyl-(2-methoxybenzyl)amino]heptyloxy]-xanthen-9-one | - |
Homo sapiens | |
3-[7-[methyl-(2,3,4-trimethoxybenzyl)amino]-heptyloxy]xanthen-9-one | - |
Homo sapiens | |
3-[7-[methyl-(2-methylbenzyl)amino]-heptyloxy]-xanthen-9-one | - |
Homo sapiens | |
3-[7-[methyl-(2-nitrobenzyl)amino]heptyloxy]-xanthen-9-one | - |
Homo sapiens | |
3-[8-(benzylmethylamino)octyloxy]xanthen-9-one | - |
Homo sapiens | |
3-[9-(benzylmethylamino)nonyloxy]xanthen-9-one | - |
Homo sapiens | |
3-[omega-(benzylmethylamino)alkoxy]xanthen-9-ones | structure-activity relationships, overview | Homo sapiens | |
6-[7-(benzylmethylamino)heptyloxy]-2,3-dimethoxyxanthen-9-one | - |
Homo sapiens | |
xanthostigmine | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
commercial preparation | from erythrocytes | Homo sapiens | - |
erythrocyte | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetylthiocholine iodide + H2O | - |
Homo sapiens | thiocholine iodide + acetate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
AChE | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8 | - |
assay at | Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0003 | - |
- |
Homo sapiens | xanthostigmine | |
0.00218 | - |
pH 8.0, 37°C | Homo sapiens | 3-[7-[(2-methoxybenzyl)methylamino]heptyloxy]-xanthen-9-one | |
0.00232 | - |
pH 8.0, 37°C | Homo sapiens | 6-[7-(benzylmethylamino)heptyloxy]-2,3-dimethoxyxanthen-9-one | |
0.00268 | - |
pH 8.0, 37°C | Homo sapiens | 3-[3-(benzylmethylamino)propoxy]xanthen-9-one | |
0.00282 | - |
pH 8.0, 37°C | Homo sapiens | 3-[7-(benzylmethylamino)-heptyloxy]xanthen-9-one | |
0.00289 | - |
pH 8.0, 37°C | Homo sapiens | 3-[6-(benzylmethylamino)hexyloxy]xanthen-9-one | |
0.00315 | - |
pH 8.0, 37°C | Homo sapiens | 3-[7-[ethyl-(2-methoxybenzyl)amino]heptyloxy]-xanthen-9-one | |
0.0034 | - |
pH 8.0, 37°C | Homo sapiens | 3-[3-[(2-methoxybenzyl)methylamino]propoxy]-xanthen-9-one | |
0.00625 | - |
pH 8.0, 37°C | Homo sapiens | 3-[4-(benzylmethylamino)butoxy]xanthen-9-one | |
0.00778 | - |
pH 8.0, 37°C | Homo sapiens | 3-[5-(benzylmethylamino)pentyloxy]xanthen-9-one | |
0.00784 | - |
pH 8.0, 37°C | Homo sapiens | 3-[7-(benzylmethylamino)heptyloxy]-6-methoxyxanthen-9-one | |
0.0103 | - |
pH 8.0, 37°C | Homo sapiens | 3-[8-(benzylmethylamino)octyloxy]xanthen-9-one | |
0.04 | - |
pH 8.0, 37°C | Homo sapiens | 3-[7-[(3-methoxybenzyl)methylamino]heptyloxy]-xanthen-9-one | |
0.127 | - |
pH 8.0, 37°C | Homo sapiens | 3-[7-[(2,5-dimethoxybenzyl)methylamino]heptyloxy]xanthen-9-one | |
0.138 | - |
pH 8.0, 37°C | Homo sapiens | 3-[7-[(2,3-dimethoxybenzyl)methylamino]heptyloxy]xanthen-9-one | |
0.152 | - |
pH 8.0, 37°C | Homo sapiens | 3-[9-(benzylmethylamino)nonyloxy]xanthen-9-one | |
0.155 | - |
pH 8.0, 37°C | Homo sapiens | 3-[7-[methyl-(2,3,4-trimethoxybenzyl)amino]-heptyloxy]xanthen-9-one | |
0.36 | - |
pH 8.0, 37°C | Homo sapiens | 3-[7-[(4-methoxybenzyl)methylamino]heptyloxy]-xanthen-9-one | |
0.388 | - |
pH 8.0, 37°C | Homo sapiens | 3-[10-(benzylmethylamino)decyloxy]xanthen-9-one | |
0.413 | - |
pH 8.0, 37°C | Homo sapiens | 3-[7-[methyl-(2-nitrobenzyl)amino]heptyloxy]-xanthen-9-one | |
0.433 | - |
pH 8.0, 37°C | Homo sapiens | 3-[7-[(2-chlorobenzyl)methylamino]-heptyloxy]-xanthen-9-one | |
0.565 | - |
pH 8.0, 37°C | Homo sapiens | 3-[7-[methyl-(2-methylbenzyl)amino]-heptyloxy]-xanthen-9-one | |
0.594 | - |
pH 8.0, 37°C | Homo sapiens | 3-[7-[(3-chlorobenzyl)methylamino]-heptyloxy]-xanthen-9-one | |
0.626 | - |
pH 8.0, 37°C | Homo sapiens | 3-[11-(benzylmethylamino)undecyloxy]xanthen-9-one | |
0.908 | - |
pH 8.0, 37°C | Homo sapiens | 3-[12-(benzylmethylamino)dodecyloxy]xanthen-9-one | |
1.05 | - |
pH 8.0, 37°C | Homo sapiens | 3-[7-[(4-chlorobenzyl)methylamino]-heptyloxy]-xanthen-9-one |