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Literature summary for 3.1.1.7 extracted from

  • Lin, G.; Liu, Y.C.; Lin, Y.F.; Wu, Y.G.
    Ortho effects in quantitative structure-activity relationships for acetylcholinesterase inhibition by aryl carbamates (2004), J. Enzyme Inhib. Med. Chem., 19, 395-401.
    View publication on PubMed
Search for more literature for 3.1.1.7

Inhibitors

Inhibitors Comment Organism Structure
2-(trifluoromethyl)phenyl butylcarbamate
-
 Electrophorus electricus
2-chlorophenyl butylcarbamate
-
 Electrophorus electricus
2-ethylphenyl butylcarbamate
-
 Electrophorus electricus
2-methoxyphenyl butylcarbamate
-
 Electrophorus electricus
2-methylphenyl butylcarbamate
-
 Electrophorus electricus
2-nitrophenyl butylcarbamate
-
 Electrophorus electricus
2-tert-butoxyphenyl butylcarbamate
-
 Electrophorus electricus
biphenyl-2-yl butylcarbamate
-
 Electrophorus electricus
additional information proposed mechanism for enzyme inhibition by N-butylcarbamates and detailed kinetics of inhibition Electrophorus electricus
phenyl butylcarbamate
-
 Electrophorus electricus

Organism

Organism UniProt Comment Textmining
Electrophorus electricus
-
 commercial preparation
-

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.002
-
 2-tert-butoxyphenyl butylcarbamate pH 7.0, 25°C Electrophorus electricus
0.0024
-
 2-nitrophenyl butylcarbamate pH 7.0, 25°C Electrophorus electricus
0.0028
-
 2-(trifluoromethyl)phenyl butylcarbamate pH 7.0, 25°C Electrophorus electricus
0.003
-
 2-methoxyphenyl butylcarbamate pH 7.0, 25°C Electrophorus electricus
0.003
-
 2-ethylphenyl butylcarbamate pH 7.0, 25°C Electrophorus electricus
0.0032
-
 biphenyl-2-yl butylcarbamate pH 7.0, 25°C Electrophorus electricus
0.0032
-
 phenyl butylcarbamate pH 7.0, 25°C Electrophorus electricus
0.004
-
 2-methylphenyl butylcarbamate pH 7.0, 25°C Electrophorus electricus
0.004
-
 2-chlorophenyl butylcarbamate pH 7.0, 25°C Electrophorus electricus