Cloned (Comment) | Organism |
---|---|
- |
Mus musculus |
Protein Variants | Comment | Organism |
---|---|---|
E81C | reporter group 5-((((2-acetyl)amino)ethyl)amino)naphthalene-1-sulfonic acid attached to cysteine | Mus musculus |
E84C | reporter group 5-((((2-acetyl)amino)ethyl)amino)naphthalene-1-sulfonic acid attached to cysteine | Mus musculus |
L76C | reporter group 5-((((2-acetyl)amino)ethyl)amino)naphthalene-1-sulfonic acid attached to cysteine | Mus musculus |
Y124C | reporter group 5-((((2-acetyl)amino)ethyl)amino)naphthalene-1-sulfonic acid attached to cysteine | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
fasciculin | binds at the mouth of the gorge, decreases the mobility of reporter groups attached to L76C and Y124C, increases the mobility of reporter groups attached to E81C and E84C | Mus musculus | |
huperzine | binds at the base of the active site gorge, has no effect on the mobility of reporter groups attached to L76C and Y124C, increases the mobility of reporter groups attached to E81C and E84C | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | P21836 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Mus musculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetylthiocholine iodide + H2O | - |
Mus musculus | thiocholine iodide + acetate | - |
? |