Activating Compound | Comment | Organism | Structure |
---|---|---|---|
acetylthiocholine | substrate activiation below 1 mM is only seen in W86F mutant but not in wild-type or D74G mutant | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
- |
Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
D74G | shows no substrate activation | Homo sapiens |
W86F | shows substrate activation at low concentration and substrate inhibition at high concentrations | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
acetylthiocholine | substrate inhibition above 1 mM | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.047 | - |
3-(acetamido)-N,N,N-trimethylanilinum | pH 8 | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
W86F and D74G mutant | Homo sapiens |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
acetylcholine + H2O = choline + acetate | mechanism | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3-(acetamido)-N,N,N-trimethylanilinum + H2O | ATMA | Homo sapiens | ? | - |
? | |
acetylthiocholine + H2O | - |
Homo sapiens | thiocholine + acetate | - |
? |