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Literature summary for 3.1.1.7 extracted from
- Characterization of acetylcholinesterase purified from the lesser grain borer, Rhyzopertha dominica (Coleoptera: Bostrichidae) (1998), Comp. Biochem. Physiol. B, 119, 205-210.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| acetyl-[beta-methyl]thiocholine | - |
Rhyzopertha dominica |  |
| acetylthiocholine | - |
Rhyzopertha dominica | |
| BW4c51 | - |
Rhyzopertha dominica | |
| ethopropazine | partially | Rhyzopertha dominica | |
| physostigmine | - |
Rhyzopertha dominica | |
| propionylthioacetylcholine | - |
Rhyzopertha dominica | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 56000 | - |
2 * 56000, SDS-PAGE | Rhyzopertha dominica |
| 107000 | - |
non-denaturing PAGE | Rhyzopertha dominica |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acetylcholine + H2O | Rhyzopertha dominica | inactivation of transmitter substance operating in cholinergic neurotransmission | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rhyzopertha dominica | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Rhyzopertha dominica |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 4.7 | - |
- |
Rhyzopertha dominica |
Storage Stability
| Storage Stability | Organism |
|---|---|
| 4°C, 20% glycerol, 3 days | Rhyzopertha dominica |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acetyl-[beta-methyl]thiocholine + H2O | - |
Rhyzopertha dominica | acetate + [beta-methyl]thiocholine | - |
? | |
| acetylcholine + H2O | inactivation of transmitter substance operating in cholinergic neurotransmission | Rhyzopertha dominica | ? | - |
? | |
| acetylthiocholine + H2O | - |
Rhyzopertha dominica | thiocholine + acetate | - |
? | |
| butyrylthiocholine + H2O | - |
Rhyzopertha dominica | butyrate + thiocholine | - |
? | |
| propionylthiocholine + H2O | - |
Rhyzopertha dominica | propanoate + thiocholine | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | 2 * 56000, SDS-PAGE | Rhyzopertha dominica |
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