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Literature summary for 3.1.1.67 extracted from
- Differential inhibition of hepatic, pancreatic, and plasma fatty acid ethyl ester synthase by tri-o-tolyl phosphate in rats (2002), Toxicol. Appl. Pharmacol., 179, 119-125.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| tri-o-tolyl phosphate | differential inhibition of hepatic, pancreatic and plasma FAEES, no inhibition of pancreatic FAEES activity | Rattus norvegicus |  |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 60000 | - |
x * 60000, FAEES from liver, Western blot analysis | Rattus norvegicus |
| 84000 | - |
x * 84000, FAEES from plasma, Western blot analysis | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
| pancreas | - |
Rattus norvegicus | - |
| plasma | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| fatty acid + ethanol | - |
Rattus norvegicus | fatty acyl ethyl ester + H2O | - |
? | |
| oleate + ethanol | - |
Rattus norvegicus | ethyl oleate + H2O | - |
? | |
| oleate + methanol | - |
Rattus norvegicus | methyl oleate + H2O | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 60000, FAEES from liver, Western blot analysis | Rattus norvegicus |
| ? | x * 84000, FAEES from plasma, Western blot analysis | Rattus norvegicus |
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