KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.12 | - |
stearate | pH 7.2 | Homo sapiens | |
0.13 | - |
arachidonate | pH 7.2 | Homo sapiens | |
0.18 | - |
palmitate | pH 7.2 | Homo sapiens | |
0.2 | - |
linoleate | pH 7.2 | Homo sapiens | |
0.22 | 0.23 | oleate | pH 7.2 | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Homo sapiens | 5829 | - |
soluble | - |
Homo sapiens | - |
- |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
26000 | - |
2 * 26000, SDS-PAGE | Homo sapiens |
54000 | - |
gel filtration under nondenaturing conditions | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
fatty acid + ethanol | Homo sapiens | nonoxidative ethanol metabolism | fatty acyl ethyl ester + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
8867fold, major enzyme form, synthase I | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
heart | ventricular myocardium | Homo sapiens | - |
myocardium | ventricular | Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Homo sapiens |
0.04433 | - |
major enzyme form | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
arachidonate + ethanol | 50% of the rate with oleate | Homo sapiens | ethyl arachidonate + H2O | - |
? | |
fatty acid + ethanol | - |
Homo sapiens | fatty acyl ethyl ester + H2O | - |
? | |
fatty acid + ethanol | nonoxidative ethanol metabolism | Homo sapiens | fatty acyl ethyl ester + H2O | - |
? | |
linoleate + ethanol | 65% of the rate with oleate | Homo sapiens | ethyl linoleate + H2O | - |
? | |
oleate + ethanol | highest activity | Homo sapiens | ethyl oleate + H2O | - |
? | |
palmitate + ethanol | 20% of the rate with oleate | Homo sapiens | ethyl palmitate + H2O | - |
? | |
stearate + ethanol | 22% of the rate with oleate | Homo sapiens | ethyl stearate + H2O | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | 2 * 26000, SDS-PAGE | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.2 | - |
assay at | Homo sapiens |