Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q16518 | - |
- |
Mus musculus | Q91ZQ5 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cone | - |
Mus musculus | - |
cone | - |
Homo sapiens | - |
General Information | Comment | Organism |
---|---|---|
physiological function | deletion of RPE65 partially suppresses cone dark adaptation. Transgenic mice expressing human RPE65 in the cones reveal no morphological or functional changes between control (RPE65-deficient) and transgenic cones, with only a slight delay in dark adaptation, possibly caused by the buffering of retinoids by RPE65 | Mus musculus |
physiological function | transgenic mice expressing human RPE65 in the cones reveal no morphological or functional changes between control (RPE65-deficient) and transgenic cones, with only a slight delay in dark adaptation, possibly caused by the buffering of retinoids by RPE65 | Homo sapiens |