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Literature summary for 3.1.1.64 extracted from
- RPE65 from cone-dominant chicken is a more efficient isomerohydrolase compared with that from rod-dominant species (2008), J. Biol. Chem., 283, 8110-8117.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli and in 293A-LRAT cells | Gallus gallus |
| expressed in Escherichia coli and in 293A-LRAT cells | Homo sapiens |
| expressed in Escherichia coli and in 293A-LRAT cells | Bos taurus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| apo-cellular retinol-binding protein type 1 | - |
Bos taurus | |
| apo-cellular retinol-binding protein type 1 | - |
Gallus gallus | |
| apo-cellular retinol-binding protein type 1 | - |
Homo sapiens | |
| N-(12-chloro-11-oxododecyl)acetamide | - |
Bos taurus |  |
| N-(12-chloro-11-oxododecyl)acetamide | - |
Gallus gallus | |
| N-(12-chloro-11-oxododecyl)acetamide | - |
Homo sapiens | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | - |
Gallus gallus | - |
- |
| microsome | - |
Homo sapiens | - |
- |
| microsome | - |
Bos taurus | - |
- |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 60927 | - |
x * 60927, calculated from amino acid sequence | Gallus gallus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
| Gallus gallus | - |
- |
- |
| Homo sapiens | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| DEAE-Sepharose column chromatography | Gallus gallus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| retinal pigment epithelium | - |
Gallus gallus | - |
| retinal pigment epithelium | - |
Homo sapiens | - |
| retinal pigment epithelium | - |
Bos taurus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| all-trans-retinyl ester + H2O | direct substrate | Gallus gallus | 11-cis-retinol + a fatty acid | - |
? | |
| all-trans-retinyl ester + H2O | direct substrate | Homo sapiens | 11-cis-retinol + a fatty acid | - |
? | |
| all-trans-retinyl ester + H2O | direct substrate | Bos taurus | 11-cis-retinol + a fatty acid | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 60927, calculated from amino acid sequence | Gallus gallus |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| retinol isomerohydrolase | - |
Gallus gallus |
| retinol isomerohydrolase | - |
Homo sapiens |
| retinol isomerohydrolase | - |
Bos taurus |
| Rpe65 | - |
Gallus gallus |
| Rpe65 | - |
Homo sapiens |
| Rpe65 | - |
Bos taurus |
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Release 2023.1 (January 2023)
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